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Table 2 Summary table illustrating the distribution of BIN1 exons and isoforms in different cell types in CNS

From: BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology

  DLPFC - Bulk RNA-seq Neuron – Immunofluorescence Exon Specific Antibody Astrocyte – Immunofluorescence Exon Specific Antibody Microglia - Purified Microglia RNA-seq Microglia – Immunofluorescence Exon Specific Antibody
Isoform 1 Yes exon 7 exon 7 No No
Isoform 2 Yes exon 7 exon 7 No No
Isoform 3 Yes exon 7 exon 7 No No
Isoform 4 No No No No No
Isoform 5 Yes exon 11, 13 exon 11, 13 No No
Isoform 6 Yes exon 11, 13 exon 11, 13 Yes exon 11, 13
Isoform 7 Yes exon 16 exon 16 No No
Isoform 8 No No No No No
Isoform 9 Yes data N/A data N/A Yes data N/A
Isoform 10 Yes data N/A data N/A Yes data N/A
Isoform 12 Yes data N/A data N/A Yes data N/A
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