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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach

Fig. 4

Associations between the six CSF candidate biomarkers for DLB and MMSE. Scatter plots of MMSE and CSF levels of (a) VGF (b) SCG2, (c) NPTX2, (d) NPTXR, (e) PDYN, (f) PCSK1N across DLB (red) and control groups (blue). Individual subject cohort 1 are depicted as squares and individual subjects from cohort 2 are depicted as triangles. Associations were assessed using Spearman partial correlation adjusted for cohort. To correct for multiple comparisons, p-values were corrected using a false discovery rate (FDR) correction. Abbreviations: DLB, Dementia with Lewy bodies; NPTX2, Neuronal pentraxin 2; NPTXR, Neuronal pentraxin receptor, PCSK1N, ProSAAS; PDYN, Proenkephalin-B; SCG2, Scretogranin-2; VGF, Neurosecretory protein VGF

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