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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer’s disease mutations but not by inhibition of BACE1

Fig. 3

Amyloid deposition. a–e Coronal brain sections from 8 to 9-month-old mice of the indicated genotypes were labeled with nuclear red (NucRed) and stained for Aβ deposits with Thioflavin S or the 3D6 antibody. Columns (a) and (e) show merges of all three stains. Column (a) depicts hemibrains (scale bar: 1.2 mm), columns (b–d) show hippocampus (top) and neocortex (bottom) (scale bars: 600 μm), and column (e) provides a magnified view (scale bar: 150 μm) of the inset in column (d)

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Molecular Neurodegeneration

ISSN: 1750-1326