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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer’s disease-related inhibitory circuit dysfunction in adults with Down syndrome

Fig. 4

Structural and functional neuroimaging correlates of CSF NPTX2 levels in DS. Correlation of CSF NPTX2 levels and cortical thickness (top) and glucose metabolism (bottom) in all DS participants. Regions in red represent significant correlations (p < 0.05). Only the clusters that survived family-wise error correction p < 0.05 are shown. Scatterplots with linear regression line (black) and standard error (gray) show the correlation between CSF NPTX2 and neuroimaging biomarkers by diagnosis in a representative cluster that survived multiple comparisons, indicated with an asterisk. Regression lines are shown for each clinical group for informative purposes (see legend)

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Molecular Neurodegeneration

ISSN: 1750-1326