Table 1 Demographics and clinical data for study participants

N

34

40

49

18

27

Mean age-at-collection (years)

51

70

37

52

52

 SD (range)

13 (24–74)

7 (52–83)

10 (22–57)

4 (45–60)

5 (42–62)

Sex (% Female)

68%

65%

47%

44%

42%

Intellectual Disability^a

None

None

80%;20%

78%;22%

67%;33%

FCSRT Immediate Total Recall

34

13

35

19

15

 SD (range), n

3 (34–48), 40

10 (0–36), 30

2 (30–36), 33

11 (0–36), 11

7 (0–32), 13

Semantic Verbal Fluency Test

22

9

10

8

7

 SD (range), n

5 (14–33), 34

4 (3–15), 30

3 (3–18), 37

2 (4–13), 12

4 (1–12), 15

CAMCOG

N/A

N/A

79

67

54

 SD (range), n

N/A

N/A

12 (51–96), 36

12 (41–80), 10

22 (2–87), 11

Mean CSF Aβ_1–42 (pg/ml)

1359

492

1089

489

504

 SD (range)

284 (1000–2034)

107 (275–690)

474 (302–2335)

146 (235–865)

160 (235–765)

Mean CSF t-tau (pg/ml)

249

781

342

972

1095

 SD (range)

63 (157–407)

423 (229–2110)

248 (86–1394)

658 (118–2565)

653 (212–3150)

Mean CSF p-tau (pg/ml)

37

137

44

173

173

 SD (range)

9 (22–55)

62 (55–351)

47 (10–277)

128 (22–564)

92 (31–354)