| Control | TauR406W | Change |
---|
Transcripts | 6742 | 7970 | + 18% |
Proteins | 1155 | 258 | −78% |
- In TauR406W animals, aging is associated with an increased number of differentially-expressed transcripts but a decreased number of proteins. Differentially-expressed transcripts and proteins were determined by comparing aged animals, stratified by genotype, analyzing elav (control) or elav > TauR406W animals separately. The total number of unique, differentially-expressed transcripts or proteins are shown based on the union of 3 comparisons (1- vs. 10-days, 10- vs. 20-days, and 1- vs. 20-days). Statistical analysis was based on a Wald test (FDR < 0.05). See Additional file 2: Tables S3 and S4 for complete results