Fig. 1
From: Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue
Amyloid and Tau autoradiography binding in 2 DS-AD in comparison to 1 EOAD and 1 control. Top row: DS-AD-1 57-year-old female with DS-AD. From left to right: Autoradiographic images showing 3H-PIB binding (a, b),3H-THK5117 binding (a’,b’) and 3H-MK6240 binding (a”,b”) on an adjacent section in HIPP and MFG. DS-AD-2 62-year-old female with DS-AD From left to right: Autoradiographic images showing 3H-PIB binding (c,d),3H-THK5117 binding (c’,d’) and 3H-MK6240 binding (c”,d”) on an adjacent section in HIPP and MFG. Bottom row: EOAD: 55-year-old female diagnosed with Alzheimer’s disease: From left to right: Autoradiographic images showing 3H-PIB binding (e,f),3H-THK5117 binding (e’,f’) and 3H-MK6240 binding (e”,f”) on an adjacent section in HIPP and MFG. CONTROL: 59-year-old control case. From left to right: Autoradiographic images showing 3H-PIB binding (g, h),3H-THK5117 binding (g’,h’) on an adjacent section in HIPP and MFG