Fig. 4
From: Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue
Linear regressions between autoradiography binding and density staining. a. 3H-THK5117 and AT8 immunostaining (Pearson r = 0.564, p < 0.001, shown in blue), and 3H-MK6240 and AT8 immunostaining (Pearson r = 0.506, p = 0.045, shown in red) in the whole cohort (AD, DS-AD, CN) in both regions (MFG + HIPP). b: 3H-PIB and Amylo-Glo (Pearson r = 0.236, p = 0.148) in the whole population (AD, DS-AD,CN) in both regions (MFG + HIPP). c: 3H-THK5117 and 3H-MK6240 (Pearson r = 0.603, p = 0.013) in the whole population (AD, DS-AD,CN) in both regions (MFG + HIPP). d: Correlation in the whole population (AD,DS-AD,CN) in both regions (MFG + HIPP) between 3H-PIB and 3H-THK5117(Pearson r = 0.463, p = 0.002)