Fig. 5
From: Cell-autonomous role of Presenilin in age-dependent survival of cortical interneurons
Normal levels of dendritic and synaptic makers in the cortex of IN-PS cDKO mice. a Left: Western blotting of neocortical lysates of IN-PS cDKO and controls at the age of 9 months. Right: Quantification analysis shows normal levels of dendritic and synaptic markers in the neocortex of IN-PS cDKO mice relative to controls (MAP2: p = 0.59, SYP: p = 0.68, SNAP25: p = 0.80, PSD95: p = 0.39, Student’s t-test). All values are normalized to β-Actin. b Left: Western blotting of hippocampal lysates of IN-PS cDKO and controls at the age of 9 months. Right: Quantification analysis shows normal levels of dendritic and synaptic markers in the hippocampus of IN-PS cDKO mice relative to controls (MAP2: p = 0.05, SYP: p = 0.68, SNAP25: p = 0.58, PSD95: p = 0.07, Student’s t-test). All values are normalized to β-Actin. All data represent mean ± SEM