Table 1 Characteristics of primary cohort
Variable | C9Plus (n = 75) | C9Minus (n = 33) | Control (n = 20) |
|---|---|---|---|
Sex, No. (% female) | 41 (54.67) | 15 (45.45) | 10 (50.00) |
Site of Onset, No. (% bulbar) | 15 (20.00) | 6 (18.18) | NA |
Age at Collection, median (IQR), y | 60.87 (55.28–65.94) | 61.25 (56.58–65.05) | 60.05 (52.05–65.26) |
Age at Onset, median (IQR), y | 59.25 (52.94–64.08) | 60.08 (55.08–63.42) | NA |
Survival after Onseta, median (IQR), y | 1.98 (1.54–3.10) | 1.99 (1.12–3.19) | NA |
Methylation, median (IQR), % | 4.05 (1.10–17.95) | 0.24 (0.15–0.33) | 0.46 (0.14–0.75) |
Expression, median (IQR), % | 73.32 (65.96–86.20) | 110.70 (93.68–132.88) | 100.00 (87.48–111.27) |
Repeat Length, median (IQR), kb | 20.05 (15.58–26.27) | NA | NA |