TY - JOUR AU - Lau, L. M. AU - Breteler, M. M. PY - 2006 DA - 2006// TI - Epidemiology of Parkinson's disease JO - Lancet Neurol VL - 5 UR - https://doi.org/10.1016/S1474-4422(06)70471-9 DO - 10.1016/S1474-4422(06)70471-9 ID - Lau2006 ER - TY - JOUR AU - Tysnes, O. B. AU - Storstein, A. PY - 2017 DA - 2017// TI - Epidemiology of Parkinson's disease JO - J Neural Transm (Vienna) VL - 124 UR - https://doi.org/10.1007/s00702-017-1686-y DO - 10.1007/s00702-017-1686-y ID - Tysnes2017 ER - TY - JOUR AU - Hatano, T. AU - Saiki, S. AU - Okuzumi, A. AU - Mohney, R. P. AU - Hattori, N. PY - 2016 DA - 2016// TI - Identification of novel biomarkers for Parkinson's disease by metabolomic technologies JO - J Neurol Neurosurg Psychiatry VL - 87 UR - https://doi.org/10.1136/jnnp-2014-309676 DO - 10.1136/jnnp-2014-309676 ID - Hatano2016 ER - TY - STD TI - Cressatti M, Juwara L, Galindez JM, Velly AM, Nkurunziza ES, Marier S, Canie O, Gornistky M, Schipper HM. Salivary microR-153 and microR-223 levels as potential diagnostic biomarkers of idiopathic Parkinson's disease. Mov Disord. 2020;35:468-77. ID - ref4 ER - TY - JOUR AU - Burte, F. AU - Houghton, D. AU - Lowes, H. AU - Pyle, A. AU - Nesbitt, S. AU - Yarnall, A. AU - Yu-Wai-Man, P. AU - Burn, D. J. AU - Santibanez-Koref, M. AU - Hudson, G. PY - 2017 DA - 2017// TI - Metabolic profiling of Parkinson's disease and mild cognitive impairment JO - Mov Disord VL - 32 UR - https://doi.org/10.1002/mds.26992 DO - 10.1002/mds.26992 ID - Burte2017 ER - TY - JOUR AU - Li, T. AU - Yang, Z. AU - Li, S. AU - Cheng, C. AU - Shen, B. AU - Le, W. PY - 2018 DA - 2018// TI - Alterations of NURR1 and cytokines in the peripheral blood mononuclear cells: combined biomarkers for Parkinson's disease JO - Front Aging Neurosci VL - 10 UR - https://doi.org/10.3389/fnagi.2018.00392 DO - 10.3389/fnagi.2018.00392 ID - Li2018 ER - TY - JOUR AU - Le, W. AU - Pan, T. AU - Huang, M. AU - Xu, P. AU - Xie, W. AU - Zhu, W. AU - Zhang, X. AU - Deng, H. AU - Jankovic, J. PY - 2008 DA - 2008// TI - Decreased NURR1 gene expression in patients with Parkinson's disease JO - J Neurol Sci VL - 273 UR - https://doi.org/10.1016/j.jns.2008.06.007 DO - 10.1016/j.jns.2008.06.007 ID - Le2008 ER - TY - JOUR AU - Yang, Z. AU - Li, T. AU - Cui, Y. AU - Li, S. AU - Cheng, C. AU - Shen, B. AU - Le, W. PY - 2019 DA - 2019// TI - Elevated plasma microRNA-105-5p level in patients with idiopathic Parkinson's disease: a potential disease biomarker JO - Front Neurosci VL - 13 UR - https://doi.org/10.3389/fnins.2019.00218 DO - 10.3389/fnins.2019.00218 ID - Yang2019 ER - TY - STD TI - Powers R, Lei S, Anandhan A, Marshall DD, Worley B, Cerny RL, Dodds ED, Huang Y, Panayiotidis MI, Pappa A, Franco R. Metabolic investigations of the molecular mechanisms associated with Parkinson's disease. Metabolites. 2017;7:22. ID - ref9 ER - TY - JOUR AU - Shao, Y. AU - Le, W. PY - 2019 DA - 2019// TI - Recent advances and perspectives of metabolomics-based investigations in Parkinson's disease JO - Mol Neurodegener VL - 14 ID - Shao2019 ER - TY - JOUR AU - Picca, A. AU - Calvani, R. AU - Landi, G. AU - Marini, F. AU - Biancolillo, A. AU - Gervasoni, J. AU - Persichilli, S. AU - Primiano, A. AU - Urbani, A. AU - Bossola, M. PY - 2019 DA - 2019// TI - Circulating amino acid signature in older people with Parkinson's disease: a metabolic complement to the EXosomes in PArkiNson disease (EXPAND) study JO - Exp Gerontol VL - 128 ID - Picca2019 ER - TY - JOUR AU - Nho, K. AU - Kueider-Paisley, A. AU - MahmoudianDehkordi, S. AU - Arnold, M. AU - Risacher, S. L. AU - Louie, G. AU - Blach, C. AU - Baillie, R. AU - Han, X. AU - Kastenmuller, G. PY - 2019 DA - 2019// TI - Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: relationship to neuroimaging and CSF biomarkers JO - Alzheimers Dement VL - 15 UR - https://doi.org/10.1016/j.jalz.2018.08.012 DO - 10.1016/j.jalz.2018.08.012 ID - Nho2019 ER - TY - JOUR AU - Kessel, S. P. AU - Aidy, S. PY - 2019 DA - 2019// TI - Bacterial metabolites Mirror altered gut microbiota composition in patients with Parkinson's disease JO - J Parkinsons Dis VL - 9 UR - https://doi.org/10.3233/JPD-191780 DO - 10.3233/JPD-191780 ID - Kessel2019 ER - TY - JOUR AU - Jawaid, A. AU - Khan, R. AU - Polymenidou, M. AU - Schulz, P. E. PY - 2018 DA - 2018// TI - Disease-modifying effects of metabolic perturbations in ALS/FTLD JO - Mol Neurodegener VL - 13 UR - https://doi.org/10.1186/s13024-018-0294-0 DO - 10.1186/s13024-018-0294-0 ID - Jawaid2018 ER - TY - JOUR AU - Ren, S. AU - Shao, Y. AU - Zhao, X. AU - Hong, C. S. AU - Wang, F. AU - Lu, X. AU - Li, J. AU - Ye, G. AU - Yan, M. AU - Zhuang, Z. PY - 2016 DA - 2016// TI - Integration of metabolomics and Transcriptomics reveals major metabolic pathways and potential biomarker involved in prostate cancer JO - Mol Cell Proteomics VL - 15 UR - https://doi.org/10.1074/mcp.M115.052381 DO - 10.1074/mcp.M115.052381 ID - Ren2016 ER - TY - JOUR AU - Han, W. AU - Sapkota, S. AU - Camicioli, R. AU - Dixon, R. A. AU - Li, L. PY - 2017 DA - 2017// TI - Profiling novel metabolic biomarkers for Parkinson's disease using in-depth metabolomic analysis JO - Mov Disord VL - 32 UR - https://doi.org/10.1002/mds.27173 DO - 10.1002/mds.27173 ID - Han2017 ER - TY - JOUR AU - Masato, A. AU - Plotegher, N. AU - Boassa, D. AU - Bubacco, L. PY - 2019 DA - 2019// TI - Impaired dopamine metabolism in Parkinson’s disease pathogenesis JO - Mol Neurodegener VL - 14 UR - https://doi.org/10.1186/s13024-019-0332-6 DO - 10.1186/s13024-019-0332-6 ID - Masato2019 ER - TY - JOUR AU - Saiki, S. AU - Hatano, T. AU - Fujimaki, M. AU - Ishikawa, K. I. AU - Mori, A. AU - Oji, Y. AU - Okuzumi, A. AU - Fukuhara, T. AU - Koinuma, T. AU - Imamichi, Y. PY - 2017 DA - 2017// TI - Decreased long-chain acylcarnitines from insufficient beta-oxidation as potential early diagnostic markers for Parkinson's disease JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/s41598-017-06767-y DO - 10.1038/s41598-017-06767-y ID - Saiki2017 ER - TY - JOUR AU - Chang, K. H. AU - Cheng, M. L. AU - Tang, H. Y. AU - Huang, C. Y. AU - Wu, Y. R. AU - Chen, C. M. PY - 2018 DA - 2018// TI - Alternations of metabolic profile and Kynurenine metabolism in the plasma of Parkinson's disease JO - Mol Neurobiol VL - 55 UR - https://doi.org/10.1007/s12035-017-0845-3 DO - 10.1007/s12035-017-0845-3 ID - Chang2018 ER - TY - JOUR AU - Schulte, E. C. AU - Altmaier, E. AU - Berger, H. S. AU - Do, K. T. AU - Kastenmuller, G. AU - Wahl, S. AU - Adamski, J. AU - Peters, A. AU - Krumsiek, J. AU - Suhre, K. PY - 2016 DA - 2016// TI - Alterations in lipid and inositol metabolisms in two dopaminergic disorders JO - PLoS One VL - 11 ID - Schulte2016 ER - TY - JOUR AU - Li, T. AU - Chiang, J. Y. PY - 2014 DA - 2014// TI - Bile acid signaling in metabolic disease and drug therapy JO - Pharmacol Rev VL - 66 ID - Li2014 ER - TY - JOUR AU - MahmoudianDehkordi, S. AU - Arnold, M. AU - Nho, K. AU - Ahmad, S. AU - Jia, W. AU - Xie, G. AU - Louie, G. AU - Kueider-Paisley, A. AU - Moseley, M. A. AU - Thompson, J. W. PY - 2019 DA - 2019// TI - Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-an emerging role for gut microbiome JO - Alzheimers Dement VL - 15 ID - MahmoudianDehkordi2019 ER - TY - JOUR AU - Kiriyama, Y. AU - Nochi, H. PY - 2019 DA - 2019// TI - The biosynthesis, signaling, and neurological functions of bile acids JO - Biomolecules. VL - 9 ID - Kiriyama2019 ER - TY - JOUR AU - Postuma, R. B. AU - Berg, D. AU - Stern, M. AU - Poewe, W. AU - Olanow, C. W. AU - Oertel, W. AU - Obeso, J. AU - Marek, K. AU - Litvan, I. AU - Lang, A. E. PY - 2015 DA - 2015// TI - MDS clinical diagnostic criteria for Parkinson's disease JO - Mov Disord VL - 30 ID - Postuma2015 ER - TY - JOUR AU - Huang, Y. AU - Chen, G. AU - Liu, X. AU - Shao, Y. AU - Gao, P. AU - Xin, C. AU - Cui, Z. AU - Zhao, X. AU - Xu, G. PY - 2014 DA - 2014// TI - Serum metabolomics study and eicosanoid analysis of childhood atopic dermatitis based on liquid chromatography-mass spectrometry JO - J Proteome Res VL - 13 ID - Huang2014 ER - TY - JOUR AU - Smilde, A. K. AU - Werf, M. J. AU - Bijlsma, S. AU - Vat, B. J. C. AU - Jellema, R. H. PY - 2005 DA - 2005// TI - Fusion of mass spectrometry-based metabolomics data JO - Anal Chem VL - 77 ID - Smilde2005 ER - TY - JOUR AU - Zhao, X. AU - Zeng, Z. AU - Chen, A. AU - Lu, X. AU - Zhao, C. AU - Hu, C. AU - Zhou, L. AU - Liu, X. AU - Wang, X. AU - Hou, X. PY - 2018 DA - 2018// TI - Comprehensive strategy to construct in-house database for accurate and batch identification of Small molecular metabolites JO - Anal Chem VL - 90 ID - Zhao2018 ER - TY - JOUR AU - Benjamini, Y. AU - Hochberg, Y. PY - 1995 DA - 1995// TI - Controlling the false discovery rate : a practical and powerful approach to multiple testing JO - J R Stat Soc VL - 57 ID - Benjamini1995 ER - TY - JOUR AU - Schisterman, E. F. AU - Perkins, N. J. AU - Liu, A. AU - Bondell, H. PY - 2005 DA - 2005// TI - Optimal cut-point and its corresponding Youden index to discriminate individuals using pooled blood samples JO - Epidemiology. VL - 16 ID - Schisterman2005 ER - TY - STD TI - Yao CH, Liu GY, Yang K, Gross RW, Patti GJ. Inaccurate quantitation of palmitate in metabolomics and isotope tracer studies due to plastics. Metabolomics. 2016;12:143. ID - ref30 ER - TY - JOUR AU - Goetz, C. G. AU - Poewe, W. AU - Rascol, O. AU - Sampaio, C. AU - Stebbins, G. T. AU - Counsell, C. AU - Giladi, N. AU - Holloway, R. G. AU - Moore, C. G. AU - Wenning, G. K. PY - 2004 DA - 2004// TI - Movement Disorder Society task force report on the Hoehn and Yahr staging scale: status and recommendations the Movement Disorder Society task force on rating scales for Parkinson's disease JO - Mov Disord VL - 19 UR - https://doi.org/10.1002/mds.20213 DO - 10.1002/mds.20213 ID - Goetz2004 ER - TY - STD TI - Graham SF, Rey NL, Ugur Z, Yilmaz A, Sherman E, Maddens M, Bahado-Singh RO, Becker K, Schulz E, Meyerdirk LK, et al. Metabolomic profiling of bile acids in an experimental model of prodromal Parkinson's disease. Metabolites. 2018;8:71. ID - ref32 ER - TY - JOUR AU - Miller, I. N. AU - Cronin-Golomb, A. PY - 2010 DA - 2010// TI - Gender differences in Parkinson's disease: clinical characteristics and cognition JO - Mov Disord VL - 25 UR - https://doi.org/10.1002/mds.23388 DO - 10.1002/mds.23388 ID - Miller2010 ER - TY - JOUR AU - Luan, H. AU - Liu, L. F. AU - Tang, Z. AU - Mok, V. C. AU - Li, M. AU - Cai, Z. PY - 2015 DA - 2015// TI - Elevated excretion of biopyrrin as a new marker for idiopathic Parkinson's disease JO - Parkinsonism Relat Disord VL - 21 UR - https://doi.org/10.1016/j.parkreldis.2015.09.009 DO - 10.1016/j.parkreldis.2015.09.009 ID - Luan2015 ER - TY - JOUR AU - Luan, H. AU - Liu, L. F. AU - Meng, N. AU - Tang, Z. AU - Chua, K. K. AU - Chen, L. L. AU - Song, J. X. AU - Mok, V. C. AU - Xie, L. X. AU - Li, M. AU - Cai, Z. PY - 2015 DA - 2015// TI - LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease JO - J Proteome Res VL - 14 UR - https://doi.org/10.1021/pr500807t DO - 10.1021/pr500807t ID - Luan2015 ER - TY - JOUR AU - Luan, H. AU - Liu, L. -. F. AU - Tang, Z. AU - Zhang, M. AU - Chua, K. -. K. AU - Song, J. -. X. AU - Mok, V. C. T. AU - Li, M. AU - Cai, Z. PY - 2015 DA - 2015// TI - Comprehensive urinary metabolomic profiling and identification of potential noninvasive marker for idiopathic Parkinson’s disease JO - Sci Rep VL - 5 UR - https://doi.org/10.1038/srep13888 DO - 10.1038/srep13888 ID - Luan2015 ER - TY - JOUR AU - Andersen, A. D. AU - Blaabjerg, M. AU - Binzer, M. AU - Kamal, A. AU - Thagesen, H. AU - Kjaer, T. W. AU - Stenager, E. AU - Gramsbergen, J. B. P. PY - 2017 DA - 2017// TI - Cerebrospinal fluid levels of catecholamines and its metabolites in Parkinson's disease: effect of l-DOPA treatment and changes in levodopa-induced dyskinesia JO - J Neurochem VL - 141 UR - https://doi.org/10.1111/jnc.13997 DO - 10.1111/jnc.13997 ID - Andersen2017 ER - TY - STD TI - Ueno SI, Saiki S, Fujimaki M, Takeshige-Amano H, Hatano T, Oyama G, Ishikawa KI, Yamaguchi A, Nojiri S, Akamatsu W, Hattori N. Zonisamide administration improves fatty acid beta-oxidation in Parkinson's disease. Cells. 2018;8:14. ID - ref38 ER - TY - JOUR AU - Lucio, M. AU - Willkommen, D. AU - Schroeter, M. AU - Sigaroudi, A. AU - Schmitt-Kopplin, P. AU - Michalke, B. PY - 2019 DA - 2019// TI - Integrative Metabolomic and Metallomic analysis in a case-control cohort with Parkinson's disease JO - Front Aging Neurosci VL - 11 UR - https://doi.org/10.3389/fnagi.2019.00331 DO - 10.3389/fnagi.2019.00331 ID - Lucio2019 ER - TY - STD TI - Shah A, Han P, Wong MY, Chang RC, Legido-Quigley C. Palmitate and stearate are increased in the plasma in a 6-OHDA model of Parkinson's disease. Metabolites. 2019;9:31. ID - ref40 ER - TY - JOUR AU - Currie, E. AU - Schulze, A. AU - Zechner, R. AU - Walther, T. C. AU - Farese, R. V. PY - 2013 DA - 2013// TI - Cellular fatty acid metabolism and cancer JO - Cell Metab VL - 18 UR - https://doi.org/10.1016/j.cmet.2013.05.017 DO - 10.1016/j.cmet.2013.05.017 ID - Currie2013 ER - TY - STD TI - Kawahata I, Bousset L, Melki R, Fukunaga K. Fatty acid-binding protein 3 is critical for alpha-Synuclein uptake and MPP(+)-induced mitochondrial dysfunction in cultured dopaminergic neurons. Int J Mol Sci. 2019;20:5358. ID - ref42 ER - TY - JOUR AU - Sharon, R. AU - Bar-Joseph, I. AU - Frosch, M. P. AU - Walsh, D. M. AU - Hamilton, J. A. AU - Selkoe, D. J. PY - 2003 DA - 2003// TI - The Formation of Highly Soluble Oligomers of α-Synuclein Is Regulated by Fatty Acids and Enhanced in Parkinson's Disease JO - Neuron VL - 37 UR - https://doi.org/10.1016/S0896-6273(03)00024-2 DO - 10.1016/S0896-6273(03)00024-2 ID - Sharon2003 ER - TY - JOUR AU - Mollenhauer, B. AU - Steinacker, P. AU - Bahn, E. AU - Bibl, M. AU - Brechlin, P. AU - Schlossmacher, M. G. AU - Locascio, J. J. AU - Wiltfang, J. AU - Kretzschmar, H. A. AU - Poser, S. PY - 2007 DA - 2007// TI - Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies JO - Neurodegener Dis VL - 4 UR - https://doi.org/10.1159/000105157 DO - 10.1159/000105157 ID - Mollenhauer2007 ER - TY - STD TI - Shioda N, Yamamoto Y, Watanabe M, Binas B, Owada Y, Fukunaga K. Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain. J Neurosci. 2010; 30:3146–55. ID - ref45 ER - TY - JOUR AU - Cheng, A. AU - Shinoda, Y. AU - Yamamoto, T. AU - Miyachi, H. AU - Fukunaga, K. PY - 2019 DA - 2019// TI - Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization JO - Brain Res VL - 1707 UR - https://doi.org/10.1016/j.brainres.2018.11.036 DO - 10.1016/j.brainres.2018.11.036 ID - Cheng2019 ER - TY - JOUR AU - Wasternack, C. AU - Feussner, I. PY - 2018 DA - 2018// TI - The Oxylipin pathways: biochemistry and function JO - Annu Rev Plant Biol VL - 69 UR - https://doi.org/10.1146/annurev-arplant-042817-040440 DO - 10.1146/annurev-arplant-042817-040440 ID - Wasternack2018 ER - TY - JOUR AU - Atone, J. AU - Wagner, K. AU - Hashimoto, K. AU - Hammock, B. D. PY - 2019 DA - 2019// TI - Prostaglandins and other lipid mediators cytochrome P450 derived epoxidized fatty acids as a therapeutic tool against neuroinflammatory diseases JO - Prostaglandins Other Lipid Mediat VL - 147 UR - https://doi.org/10.1016/j.prostaglandins.2019.106385 DO - 10.1016/j.prostaglandins.2019.106385 ID - Atone2019 ER - TY - JOUR AU - Ren, Q. AU - Ma, M. AU - Yang, J. AU - Nonaka, R. AU - Yamaguchi, A. AU - Ishikawa, K. -. I. AU - Kobayashi, K. AU - Murayama, S. AU - Hwang, S. H. AU - Saiki, S. PY - 2018 DA - 2018// TI - Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson’s disease JO - Proceed Nat Acad Sci VL - 115 UR - https://doi.org/10.1073/pnas.1802179115 DO - 10.1073/pnas.1802179115 ID - Ren2018 ER - TY - JOUR AU - Rosa, A. I. AU - Duarte-Silva, S. AU - Silva-Fernandes, A. AU - Nunes, M. J. AU - Carvalho, A. N. AU - Rodrigues, E. AU - Gama, M. J. AU - Rodrigues, C. M. P. AU - Maciel, P. AU - Castro-Caldas, M. PY - 2018 DA - 2018// TI - Tauroursodeoxycholic acid improves motor symptoms in a mouse model of Parkinson's disease JO - Mol Neurobiol VL - 55 ID - Rosa2018 ER - TY - JOUR AU - Abdelkader, N. F. AU - Safar, M. M. AU - Salem, H. A. PY - 2016 DA - 2016// TI - Ursodeoxycholic acid ameliorates apoptotic Cascade in the rotenone model of Parkinson's disease: modulation of mitochondrial perturbations JO - Mol Neurobiol VL - 53 ID - Abdelkader2016 ER - TY - STD TI - Mortiboys H, Furmston R, Bronstad G, Aasly J, Elliott C, Bandmann O. UDCA exerts beneficial effect on mitochondrial dysfunction in LRRK2(G2019S) carriers and in vivo. Neurology. 2015;85:846-52. ID - ref52 ER - TY - JOUR AU - Barrasa, J. I. AU - Olmo, N. AU - Pérez-Ramos, P. AU - Santiago-Gómez, A. AU - Lecona, E. AU - Turnay, J. AU - Antonia, L. M. PY - 2011 DA - 2011// TI - Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells JO - Apoptosis VL - 16 ID - Barrasa2011 ER - TY - JOUR AU - Bedarf, J. R. AU - Hildebrand, F. AU - Coelho, L. P. AU - Sunagawa, S. AU - Bahram, M. AU - Goeser, F. AU - Bork, P. AU - Wullner, U. PY - 2017 DA - 2017// TI - Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naive Parkinson's disease patients JO - Genome Med VL - 9 ID - Bedarf2017 ER - TY - JOUR AU - Donia, M. S. AU - Fischbach, M. A. PY - 2015 DA - 2015// TI - HUMAN MICROBIOTA. Small molecules from the human microbiota JO - Science VL - 349 ID - Donia2015 ER - TY - BOOK AU - Cirstea, M. S. AU - Yu, A. C. AU - Golz, E. AU - Sundvick, K. AU - Kliger, D. AU - Radisavljevic, N. AU - Foulger, L. H. AU - Mackenzie, M. AU - Huan, T. AU - Finlay, B. B. AU - Appel-Cresswell, S. PY - 2020 DA - 2020// TI - Microbiota Composition and Metabolism Are Associated With Gut Function in Parkinson's Disease. Movement Disorders ID - Cirstea2020 ER - TY - JOUR AU - Lin, A. AU - Zheng, W. AU - He, Y. AU - Tang, W. AU - Wei, X. AU - He, R. AU - Huang, W. AU - Su, Y. AU - Huang, Y. AU - Zhou, H. AU - Xie, H. PY - 2018 DA - 2018// TI - Gut microbiota in patients with Parkinson's disease in southern China JO - Parkinsonism Relat Disord VL - 53 UR - https://doi.org/10.1016/j.parkreldis.2018.05.007 DO - 10.1016/j.parkreldis.2018.05.007 ID - Lin2018 ER - TY - JOUR AU - Zierer, J. AU - Jackson, M. A. AU - Kastenmuller, G. AU - Mangino, M. AU - Long, T. AU - Telenti, A. AU - Mohney, R. P. AU - Small, K. S. AU - Bell, J. T. AU - Steves, C. J. PY - 2018 DA - 2018// TI - The fecal metabolome as a functional readout of the gut microbiome JO - Nat Genet VL - 50 UR - https://doi.org/10.1038/s41588-018-0135-7 DO - 10.1038/s41588-018-0135-7 ID - Zierer2018 ER - TY - JOUR AU - Sankowski, B. AU - Księżarczyk, K. AU - Raćkowska, E. AU - Szlufik, S. AU - Koziorowski, D. AU - Giebułtowicz, J. PY - 2020 DA - 2020// TI - Higher cerebrospinal fluid to plasma ratio of p-cresol sulfate and indoxyl sulfate in patients with Parkinson’s disease JO - Clin Chim Acta VL - 501 UR - https://doi.org/10.1016/j.cca.2019.10.038 DO - 10.1016/j.cca.2019.10.038 ID - Sankowski2020 ER - TY - STD TI - Diether N, Willing B. Microbial fermentation of dietary protein: an important factor in diet–microbe–host interaction. Microorganisms. 2019;7:19. ID - ref60 ER - TY - JOUR AU - Roager, H. M. AU - Hansen, L. B. AU - Bahl, M. I. AU - Frandsen, H. L. AU - Carvalho, V. AU - Gøbel, R. J. AU - Dalgaard, M. D. AU - Plichta, D. R. AU - Sparholt, M. H. AU - Vestergaard, H. PY - 2016 DA - 2016// TI - Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut JO - Nat Microbiol VL - 1 ID - Roager2016 ER - TY - JOUR AU - Sun, M. F. AU - Shen, Y. Q. PY - 2018 DA - 2018// TI - Dysbiosis of gut microbiota and microbial metabolites in Parkinson's disease JO - Ageing Res Rev VL - 45 ID - Sun2018 ER - TY - JOUR AU - Scheperjans, F. AU - Aho, V. AU - Pereira, P. A. AU - Koskinen, K. AU - Paulin, L. AU - Pekkonen, E. AU - Haapaniemi, E. AU - Kaakkola, S. AU - Eerola-Rautio, J. AU - Pohja, M. PY - 2015 DA - 2015// TI - Gut microbiota are related to Parkinson's disease and clinical phenotype JO - Mov Disord VL - 30 ID - Scheperjans2015 ER - TY - JOUR AU - Havelund, J. F. AU - Andersen, A. D. AU - Binzer, M. AU - Blaabjerg, M. AU - Heegaard, N. H. H. AU - Stenager, E. AU - Faergeman, N. J. AU - Gramsbergen, J. B. PY - 2017 DA - 2017// TI - Changes in kynurenine pathway metabolism in Parkinson patients with L-DOPA-induced dyskinesia JO - J Neurochem VL - 142 ID - Havelund2017 ER - TY - JOUR AU - Dodd, D. AU - Spitzer, M. H. AU - Treuren, W. AU - Merrill, B. D. AU - Hryckowian, A. J. AU - Higginbottom, S. K. AU - Le, A. AU - Cowan, T. M. AU - Nolan, G. P. AU - Fischbach, M. A. AU - Sonnenburg, J. L. PY - 2017 DA - 2017// TI - A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites JO - Nature. VL - 551 ID - Dodd2017 ER - TY - JOUR AU - Roager, H. M. AU - Licht, T. R. PY - 2018 DA - 2018// TI - Microbial tryptophan catabolites in health and disease JO - Nat Commun VL - 9 ID - Roager2018 ER - TY - JOUR AU - Hasegawa, S. AU - Goto, S. AU - Tsuji, H. AU - Okuno, T. AU - Asahara, T. AU - Nomoto, K. AU - Shibata, A. AU - Fujisawa, Y. AU - Minato, T. AU - Okamoto, A. PY - 2015 DA - 2015// TI - Intestinal Dysbiosis and lowered serum lipopolysaccharide-binding protein in Parkinson's disease JO - PLoS One VL - 10 ID - Hasegawa2015 ER - TY - JOUR AU - Krishnan, S. AU - Ding, Y. AU - Saedi, N. AU - Choi, M. AU - Sridharan, G. V. AU - Sherr, D. H. AU - Yarmush, M. L. AU - Alaniz, R. C. AU - Jayaraman, A. AU - Lee, K. PY - 2018 DA - 2018// TI - Gut microbiota-derived tryptophan metabolites modulate inflammatory response in hepatocytes and macrophages JO - Cell Rep VL - 23 ID - Krishnan2018 ER - TY - STD TI - Kim DC, Quang TH, Yoon C-S, Ngan NTT, Lim S-I, Lee S-Y, Kim Y-C, Oh H. Anti-neuroinflammatory activities of indole alkaloids from kanjang (Korean fermented soy source) in lipopolysaccharide-induced BV2 microglial cells. Food Chem. 2016; 213:69–75. ID - ref69 ER - TY - JOUR AU - Ascherio, A. AU - Schwarzschild, M. A. PY - 2016 DA - 2016// TI - The epidemiology of Parkinson's disease: risk factors and prevention JO - Lancet Neurol VL - 15 UR - https://doi.org/10.1016/S1474-4422(16)30230-7 DO - 10.1016/S1474-4422(16)30230-7 ID - Ascherio2016 ER - TY - JOUR AU - Fujimaki, M. AU - Saiki, S. AU - Li, Y. AU - Kaga, N. AU - Taka, H. AU - Hatano, T. AU - Ishikawa, K. -. I. AU - Oji, Y. AU - Mori, A. AU - Okuzumi, A. PY - 2018 DA - 2018// TI - Serum caffeine and metabolites are reliable biomarkers of early Parkinson disease JO - Neurology VL - 90 UR - https://doi.org/10.1212/WNL.0000000000004888 DO - 10.1212/WNL.0000000000004888 ID - Fujimaki2018 ER - TY - STD TI - Takeshige-Amano H, Saiki S, Fujimaki M, Ueno SI, Li Y, Hatano T, Ishikawa KI, Oji Y, Mori A, Okuzumi A, et al. Shared metabolic profile of caffeine in Parkinsonian disorders. Mov Disord. 2020;35:1438-47. ID - ref72 ER - TY - JOUR AU - Costa, C. M. AU - Oliveira, G. L. AU - Fonseca, A. C. S. AU - Lana, R. C. AU - Polese, J. C. AU - Pernambuco, A. P. PY - 2019 DA - 2019// TI - Levels of cortisol and neurotrophic factor brain-derived in Parkinson's disease JO - Neurosci Lett VL - 708 UR - https://doi.org/10.1016/j.neulet.2019.134359 DO - 10.1016/j.neulet.2019.134359 ID - Costa2019 ER - TY - JOUR AU - Soares, N. M. AU - Pereira, G. M. AU - Altmann, V. AU - Almeida, R. M. M. AU - Rieder, C. R. M. PY - 2018 DA - 2018// TI - Cortisol levels, motor, cognitive and behavioral symptoms in Parkinson’s disease: a systematic review JO - J Neural Transm VL - 126 UR - https://doi.org/10.1007/s00702-018-1947-4 DO - 10.1007/s00702-018-1947-4 ID - Soares2018 ER - TY - JOUR AU - Kim, S. T. AU - Ji, H. C. AU - Jin, W. C. AU - Kim, S. W. AU - Hwang, O. PY - 2005 DA - 2005// TI - Immobilization stress causes increases in tetrahydrobiopterin, dopamine, and neuromelanin and oxidative damage in the nigrostriatal system JO - J Neurochem VL - 95 UR - https://doi.org/10.1111/j.1471-4159.2005.03342.x DO - 10.1111/j.1471-4159.2005.03342.x ID - Kim2005 ER - TY - JOUR AU - Ruzicka, F. AU - Jech, R. AU - Novakova, L. AU - Urgosik, D. AU - Bezdicek, O. AU - Vymazal, J. AU - Ruzicka, E. PY - 2015 DA - 2015// TI - Chronic stress-like syndrome as a consequence of medial site subthalamic stimulation in Parkinson's disease JO - Psychoneuroendocrinology. VL - 52 UR - https://doi.org/10.1016/j.psyneuen.2014.12.001 DO - 10.1016/j.psyneuen.2014.12.001 ID - Ruzicka2015 ER - TY - JOUR AU - Alam, M. AU - Schmidt, W. PY - 2004 DA - 2004// TI - Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease JO - Physiol Behav VL - 83 UR - https://doi.org/10.1016/j.physbeh.2004.08.010 DO - 10.1016/j.physbeh.2004.08.010 ID - Alam2004 ER - TY - JOUR AU - Mesches, M. H. AU - Fleshner, M. AU - Heman, K. L. AU - Rose, G. M. AU - Diamond, D. M. PY - 1999 DA - 1999// TI - Exposing rats to a predator blocks primed burst potentiation in the Hippocampus in vitro JO - J Neurosci VL - 19 UR - https://doi.org/10.1523/JNEUROSCI.19-14-j0004.1999 DO - 10.1523/JNEUROSCI.19-14-j0004.1999 ID - Mesches1999 ER - TY - STD TI - Takahashi T, Kimoto T, Tanabe N, Hattori TA, Yasumatsu N, Kawato S. Corticosterone acutely prolonged N-methyl-d-aspartate receptor-mediated Ca2+ elevation in cultured rat hippocampal neurons. J Neurochem. 2010;83:1441-51. ID - ref79 ER - TY - STD TI - Liu X, Chen J, Guan T, Yao H, Zhang W, Guan Z, Wang Y. miRNAs and target genes in the blood as biomarkers for the early diagnosis of Parkinson’s disease. BMC Syst Biol. 2019;13:10. ID - ref80 ER - TY - JOUR AU - Wang, X. AU - Zhu, Y. AU - Wang, S. AU - Wang, Z. AU - Sun, H. AU - He, Y. AU - Yao, W. PY - 2020 DA - 2020// TI - Effects of eplerenone on cerebral aldosterone levels and brain lesions in spontaneously hypertensive rats JO - Clin Exp Hypertens VL - 42 UR - https://doi.org/10.1080/10641963.2020.1723615 DO - 10.1080/10641963.2020.1723615 ID - Wang2020 ER - TY - JOUR AU - Mascolo, A. AU - Sessa, M. AU - Scavone, C. AU - Angelis, A. D. AU - Capuano, A. PY - 2016 DA - 2016// TI - New and old roles of the peripheral and brain renin-angiotensin-aldosterone system (RAAS): focus on cardiovascular and neurological diseases JO - Int J Cardiol VL - 227 UR - https://doi.org/10.1016/j.ijcard.2016.10.069 DO - 10.1016/j.ijcard.2016.10.069 ID - Mascolo2016 ER -