Fig. 4
From: Comprehensive metabolic profiling of Parkinson’s disease by liquid chromatography-mass spectrometry
Impacts of drug therapies on plasma metabolome of PD. a PLS-DA score plot of DN-PD and DO-PD in cohort 2. R2X = 0.179, R2Y = 0.863, Q2 = 0.323. CV-ANOVA data: p = 0.0030, F factor = 5.0488. b Volcano plot of the significantly changed metabolites in the plasma of PD patients after L-dopa treatment. c Heat map of differential metabolites between treated PD and DN-PD, which showed possible drug effects to the plasma metabolome