Fig. 2

Altered oscillatory activities in the OB of APP/PS1 mice. a Schematic diagram showing in vivo LFP recording in the OB. b-c Representative traces of extracellular recordings showing theta, beta and gamma oscillations in the OB of 3–5 month-old WT and APP/PS1 mice. d Oscillatory power in the theta band is significantly reduced in the OB of APP/PS1 mice compared to WT controls (p = 0.004). e Identical power in the beta band of WT and APP/PS1 mice (p = 0.386). f Significantly increased power in the low-gamma band (p = 0.011). g High-gamma power did not differ significantly in APP/PS1 mice compared to WT controls (p = 0.06) (n = 17 for WT and 18 for APP/PS1). Values represent mean ± SEM. Two-sample t-test. *p < 0.05, **p < 0.01