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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4

Fig. 2

cPLA2 and p-cPLA2 levels in 8-month old ApoE3-TR and ApoE4-TR mouse brains. The cortex of 8-month old APOE3-TR and ApoE4-TR mice were collected. a, cPLA2 mRNA level in the cortex was detected by qPCR. b, p-cPLA2 and total cPLA2 protein levels in the cortex were detected by western blot. c. Densitometric quantification from b. d, cPLA2 activity in mouse cortex homogenates were measured by cPLA2 activity assay kit. e, LTB4 levels in mouse cortical homogenates were measured by LTB4 assay kit. (n = 5 for each genotype, 3 males and 2 females)

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