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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease

Fig. 2

Correlation analyses between [18F]BCPP-EF SUVR and [11C]PBB3 BPND, [11C] PiB SUVR, or neuropsychological battery scores in the Braak stage I-II region of interest (ROI) in patients with AD. a Brain area of Braak stage I-II ROI overlaid on the Montreal Neurological Institute 152 reference template. b The regional [18F]BCPP-EF SUVR in AD (n = 32) was significant lower than that in the controls (n = 17). c The regional [11C]PBB3 BPND in AD (n = 32) was significant higher than that in the controls (n = 18). d There was significant negative correlation of [18F] BCPP-EF SUVR with [11C]PBB3 BPND (n = 16). e Correlation of [18F]BCPP-EF SUVR with [11C] PiB SUVR failed to reach significance (n = 32). f, g, h There was significant positive correlation of [18F] BCPP-EF SUVR with Wechsler Memory Scale-Revised logical memory score (n = 25), but not Mini-Mental Examination score (n = 32) or Frontal Assessment Battery score (n = 25). i, j, k There was no significant positive correlation of [11C]PBB3 BPND with Mini-Mental Examination score, Wechsler Memory Scale-Revised logical memory score, or Frontal Assessment Battery score (n = 16)

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