Symbol | Region Annotation | CHR | Region Location | Peak Location (PW, NBB) | MetaP | LFC PW, NBB | PeakName PW, NBB | Proportion Significant |
---|---|---|---|---|---|---|---|---|
Common hypoacetylated regions | ||||||||
PTPRH | introns | 19 | 55,718,568–55,720,750 | 55,720,288–55,722,414, 55,717,912–55,719,103 | 1.7E-07 | −0.81, −0.94 | Peak_20188, Peak_15767 | 3p/4 (0.8) |
JUP | introns | 17 | 39,681,526–39,923,630 | 39,805,764–39,808,133, 39,807,092–39,808,006 | 1.1E-05 | −0.43, − 0.99 | Peak_53983, Peak_81536 | 5p/10p (0.5) |
Common hyperacetylated regions (top 15) | ||||||||
DLG2a | exons | 11 | 83,874,504–83,874,554 | 83,873,551–83,879,844, 83,873,666–83,877,544 | 7.7E-12 | 0.68, 1.05 | Peak_21808, Peak_40741 | 30p/49p(0.6) |
KIT | exons | 4 | 55,604,595–55,606,881 | 55,606,747–55,609,274, 55,606,782–55,609,553 | 8.1E-11 | 0.63, 1.26 | Peak_21777, Peak_37103 | 2/3p (0.7) |
CNTNAP2 | exons | 7 | 147,336,198–147,336,398 | 147,333,973–147,338,260, 147,333,944–147,337,213 | 6.2E-09 | 0.51, 1.07 | Peak_44999, Peak_47588 | 11/18p (0.6) |
RNF216 | introns | 7 | 5,681,008–5,692,043 | 5,679,685–5,685,127, 5,688,370–5,705,729 | 1.2E-08 | 0.6, 0.53 | Peak_38631, Peak_12618 | 11p/16 (0.7) |
FRMD5 | introns | 15 | 44,216,508–44,393,656 | 44,260,324–44,263,821, 44,244,249–44,247,825 | 1.6E-08 | 0.68, 0.67 | Peak_18018, Peak_18744 | 12p/17p(0.7) |
SOX2-OT | introns | 3 | 181,328,718–181,417,385 | 181,358,880–181,360,150, 181,341,154–181,348,014 | 1.7E-08 | 0.55, 0.91 | Peak_43667, Peak_31549 | 9/12 (0.8) |
MAGI2 | 1to5kb | 7 | 78,120,338–78,124,337 | 78,121,257–78,128,843, 78,115,190–78,121,170 | 2.2E-08 | 0.4, 0.93 | Peak_18816, Peak_24042 | 9p/23 (0.4) |
PPP2R2B | introns | 5 | 146,080,706–146,460,621 | 146,383,635–146,384,203, 146,459,075–146,469,815 | 2.8E-08 | 1.3, 0.52 | Peak_135972, Peak_17645 | 17p/27p(0.6) |
KCNH1 | introns | 1 | 210,948,887–210,970,849 | 210,966,438–210,969,215, 210,946,491–210,950,181 | 3.8E-08 | 0.55, 1.0 | Peak_51838, Peak_38212 | 9/18p (0.5) |
CDH1 | introns | 16 | 68,835,797–68,842,326 | 68,840,159–68,841,130, 68,782,065–68,837,136 | 4.8E-08 | 0.84, 0.37 | Peak_66179, Peak_3389 | 5/7p (0.7) |
MAP 4 K4a | introns | 2 | 102,315,001–102,407,181 | 102,330,963–102,334,475, 102,367,013–102,375,949 | 5.2E-08 | 0.54, 0.62 | Peak_30093, Peak_9009 | 10p/24p(0.4) |
METTL24 | introns | 6 | 110,644,076–110,729,536 | 110,656,829–110,661,962, 110,685,537–110,688,887 | 5.4E-08 | 0.48, 0.97 | Peak_22739, Peak_27591 | 8/13p(0.6) |
PIP4K2A | introns | 10 | 22,898,647–23,003,111 | 22,934,570–22,952,399, 22,957,818–22,962,517 | 5.6E-08 | 0.58, 0.52 | Peak_22480, Peak_27954 | 9p/18p(0.5) |
SIK3 | introns | 11 | 116,827,781–116,968,858 | 116,825,819–116,835,556, 116,846,923–116,884,577 | 5.8E-08 | 0.6, 0.49 | Peak_21504, Peak_11226 | 13p/16p(0.8) |
DOCK10 | introns | 2 | 225,796,386–225,906,968 | 225,798,681–225,800,264, 225,845,772–225,849,871 | 8.1E-08 | 0.61, 0.77 | Peak_94440, Peak_22866 | 6/10p(0.6) |
Common hyperacetylated regions (additional GWAS hits) | ||||||||
CRHR1a | introns | 17 | 43,707,525–43,750,192 | 43,726,544–43,728,643, 43,741,886–43,747,152 | 2.0E-07 | 0.43, 0.83 | Peak_74390, Peak_30944 | 6/14p(0.4) |
MBNL2a | introns | 13 | 97,873,814–97,927,885 | 97,919,075–97,922,481, 97,906,667–97,916,758 | 1.2E-05 | 0.44, 0.44 | Peak_29656, Peak_16279 | 14p/22p(0.6) |