Table 2 Participant characteristics separated by brain amyloid status
Amyloid Negative (N = 253) | Amyloid Positive (N = 161) | |
|---|---|---|
Age (P < 0.0001) | ||
Mean (SD) [N] | 67.7 (8.1) [253] | 73.6 (7.4) [161] |
Sex (P = 0.0139) | ||
Female [N] | 63.6% [253] | 50.9% [161] |
Ethnicity (P = 0.5734) | ||
Hispanic [N] | 21.7% [198] | 24.5% [110] |
Race | ||
White | 176 | 97 |
Black or African American | 8 | 5 |
Asian | 2 | 0 |
American Indian or Alaska Native | 1 | 1 |
Education (P = 0.4080) | ||
Mean years (SD) [N] | 16.3 (2.4) [170] | 16.1 (2.5) [85] |
ApoE4 distribution within subgroup | ||
No E4 [N] | 71.5% [181] | 32.3% [52] |
One E4 [N] | 21.7% [55] | 50.9% [82] |
Two E4 [N] | 6.7% [17] | 16.8% [27] |
CDR (P < 0.0001) | ||
Percent CDR = 0 [N] | 79.8% [84] | 32% [75] |
MMSE (P < 0.0001) | ||
Percent MMSE = 27–30 [N] | 95.4% [152] | 60.6% [71] |
mean (sd) | 29.4 (1.6) | 26.2 (4.5) |
Abeta42/40 (P < 0.0001) | ||
mean (sd) | 0.101 (0.010) | 0.090 (0.010) |
min | 0.072 | 0.059 |
max | 0.126 | 0.148 |
Abeta42 (pg/mL) (P < 0.0001) | ||
mean (sd) | 44.477 (8.637) | 40.421 (9.698) |
min | 10.984 | 23.985 |
max | 82.494 | 103.882 |
Abeta40 (pg/mL) (P = 0.22) | ||
mean (sd) | 440.435 (81.870) | 452.325 (103.933) |
min | 134.985 | 270.455 |
max | 893.672 | 1219.238 |