Fig. 5
From: Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy
CRND8 mice show increased expression of Il6ra, Il6st, Il10ra, Il10rb, Trem2 and Cst7 mRNAs as they age. a RNAseq of the forebrain from 3, 6, 12 and 20-Month-old TgCRND8 mice and age matched littermate non-Tg mice. Each scatterplot shows data for the Fpkm values of the Tg and non-Tg at each age for the mRNA indicated. All the data underlying these analyses, detailed methods and the analyses themselves is found at https://adknowledgeportal.synapse.org/Explore/Studies?Study=syn3157182. b Summary statistics in terms of log 2 fold change (log2FC) (TgCRND8 vs. non-Tg) and adjusted p-values (padj) are shown for each age