Table 3 Intraocular pressure elevation in glaucomatous eyes
Time after Microbead Injection | Treatment | N | Mean IOP (mm Hg) ± SEM | |
|---|---|---|---|---|
Glaucoma | Control | |||
1 week | Sham | 12 | 19 ± 0.5 | 10 ± 0.4 |
Vehicle | 10 | 20 ± 0.4 | 11 ± 0.9 | |
Compound C | 9 | 20 ± 0.8 | 11 ± 0.4 | |
siCTL | 9 | 19 ± 1.0 | 11 ± 0.5 | |
siAMPK | 9 | 20 ± 0.5 | 11 ± 0.8 | |
siAMPK + Rapamycin | 9 | 21 ± 0.4 | 12 ± 0.6 | |
2 weeks | Sham | 14 | 20 ± 0.2 | 11 ± 0.5 |
Vehicle | 10 | 20 ± 0.6 | 11 ± 0.2 | |
Compound C | 9 | 24 ± 0.8 | 12 ± 0.8 | |
siCTL | 9 | 19 ± 0.8 | 10 ± 0.9 | |
siAMPK | 9 | 21 ± 0.5 | 11 ± 0.5 | |
siAMPK + Rapamycin | 9 | 22 ± 0.5 | 11 ± 0.4 | |
3 weeks | Sham | 10 | 21 ± 0.5 | 11 ± 0.8 |
siCTL | 9 | 20 ± 0.4 | 11 ± 0.8 | |
siAMPK | 9 | 19 ± 0.7 | 12 ± 0.2 | |