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Table 3 Logistic regression models to evaluate risk factors for cognitive impairment as indicated by TICS-40 ≤ 20 in COVID-19 patients

From: Post-infection cognitive impairments in a cohort of elderly patients with COVID-19

Variables Univariable ORs(95 %CI) P value Multivariable ORs(95 %CI) P value
Age, year 1.030(1.009–1.052) 0.005   
Sex, male 1.235(0.887–1.721) 0.212   
Education, year 1.000(0.971–1.030) 0.987   
BMI, kg/m2 1.055(0.957–1.163) 0.279   
Severe, vs. non-severe 9.311(6.518–13.300) < 0.001 6.507(4.411–9.599) < 0.001
ICU admission, vs. no 8.601(5.326–13.890) < 0.001   
High flow oxygen therapy, vs. no 1.901(1.324–2.727) < 0.001   
Delirium, vs. no 7.850(5.076–12.139) < 0.001 3.714(2.247–6.136) < 0.001
Coexisting disorder, vs. no
 Hypertension 1.278(0.915–1.787) 0.150   
 Diabetes 1.149(0.768–1.718) 0.500   
 Hyperlipidaemia 1.023(0.592–1.766) 0.935   
 Stroke history 3.329(1.989–5.572) < 0.001   
 Coronary heart disease 1.725(1.134–2.622) 0.011   
 COPD 4.733(3.169–7.068) < 0.001 4.224(2.693–6.625) < 0.001
  1. Dependent variables: TICS-40 score ≤ 20
  2. Independent variables: age, sex, severity, ICU admission, high flow oxygen therapy, delirium, hypertension, stroke, coronary heart disease, COPD
  3. Abbreviations: BMI body mass index, ICU intensive care unit, COPD Chronic Obstructive Pulmonary Disease