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Table 3 Logistic regression models to evaluate risk factors for cognitive impairment as indicated by TICS-40 ≤ 20 in COVID-19 patients

From: Post-infection cognitive impairments in a cohort of elderly patients with COVID-19

Variables

Univariable ORs(95 %CI)

P value

Multivariable ORs(95 %CI)

P value

Age, year

1.030(1.009–1.052)

0.005

  

Sex, male

1.235(0.887–1.721)

0.212

  

Education, year

1.000(0.971–1.030)

0.987

  

BMI, kg/m2

1.055(0.957–1.163)

0.279

  

Severe, vs. non-severe

9.311(6.518–13.300)

< 0.001

6.507(4.411–9.599)

< 0.001

ICU admission, vs. no

8.601(5.326–13.890)

< 0.001

  

High flow oxygen therapy, vs. no

1.901(1.324–2.727)

< 0.001

  

Delirium, vs. no

7.850(5.076–12.139)

< 0.001

3.714(2.247–6.136)

< 0.001

Coexisting disorder, vs. no

 Hypertension

1.278(0.915–1.787)

0.150

  

 Diabetes

1.149(0.768–1.718)

0.500

  

 Hyperlipidaemia

1.023(0.592–1.766)

0.935

  

 Stroke history

3.329(1.989–5.572)

< 0.001

  

 Coronary heart disease

1.725(1.134–2.622)

0.011

  

 COPD

4.733(3.169–7.068)

< 0.001

4.224(2.693–6.625)

< 0.001

  1. Dependent variables: TICS-40 score ≤ 20
  2. Independent variables: age, sex, severity, ICU admission, high flow oxygen therapy, delirium, hypertension, stroke, coronary heart disease, COPD
  3. Abbreviations: BMI body mass index, ICU intensive care unit, COPD Chronic Obstructive Pulmonary Disease