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Table 2 Differential expression data for apolipoproteins in EV samples isolated by UC or NBI

From: Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis

Protein name Accession number UC, average LFQ(107)a NBI, average LFQ(107)a Fold change
UC/NBIb
Apolipoprotein A-I APOA1_HUMAN 249 ± 21 57 ± 5.5 4.37*
Apolipoprotein A-II APOA2_HUMAN 2.8 ± 0.4 0.1 ± 0.0 18*
Apolipoprotein A-IV APOA4_HUMAN 6.9 ± 1.5 ND
Apolipoprotein B-100 APOB_HUMAN 628 ± 14 64 ± 8.2 9.8*
Apolipoprotein C-I APOC1_HUMAN 0.6 ± 0.0 ND
Apolipoprotein C-II APOC2_HUMAN 0.1 ± 0.0 ND
Apolipoprotein C-III APOC3_HUMAN 4.0 ± 0.3 ND
Apolipoprotein D APOD_HUMAN 4.7 ± 0.7 ND
Apolipoprotein E APOE_HUMAN 7.0 ± 0.7 ND
Apolipoprotein L1 APOL1_HUMAN 0.4 ± 0.0 ND
Apolipoprotein M APOLM_HUMAN 0.1 ± 0.0 ND
Apolipoprotein(a) APOA_HUMAN 0.5 ± 0.1 ND
  1. (a) Label-free quantification (LFQ) based on average normalized peak intensity ± SEM of samples isolated by UC (3: #1UC, #2UC, #3UC) or NBI (3, #1NBI, #2NBI, #3NBI); (b) fold-changes in expression between the samples isolated by UC and NBI; *, p < 0.05, by Wilcoxon-Mann-Whitney test. ND not determined, proteins not found in NBI samples