Fig. 1
From: Cellular and pathological heterogeneity of primary tauopathies
Various tau inclusions in primary tauopathies and AD. (A-C) PiD. Neuronal Pick bodies stain positive for 3R tau (A) while negative for 4R tau (B). White matter oligodendroglial inclusions (C). (D-F) PSP. Neuronal globose tangle (D). Tufted astrocyte (E). Oligodendroglial coiled bodies (F). (G-I) CBD. Ballooned neuron (G). Astrocytic plaque (H). Neuropil tau threads (I). (J-L) GGT. GAIs (upper right) and neuronal pretangles (lower left) (J). Higher magnification of GAIs (K). GOIs (L). (M-O) AGD. Argyrophilic grains (inset shows ballooned neuron) (M). White matter oligodendroglial coiled body (N). Bush-like astrocyte (O). (P-R) ARTAG. Thorn-shaped astrocytes in subpial (P), perivascular (Q), and subependymal regions (R). (S-U) AD. NFT (S). Neuropil tau threads (T). Dystrophic neurites in a neuritic plaque (U). Immunoreactivity to RD3 (3R tau) (A), RD4 (4R tau) (B, M-O), and CP13 (pS202 tau) (C-L, P-U). Asterisks denote the crest of the gyrus