Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques

Table 1 Information on the hiPSC lines.

hiPSC line	hiPSC name	Ethnicity	Gender	Age of onset	Age at skin biopsy	Disease status (CDR at biopsy)	APOE genotype	Genetic modification
1	TCW1E33-1F1	Caucasian	F	64	72	AD (2)	E4/E4	E3/E3
2	TCW1E44-2C2	Caucasian	F	64	72	AD (2)	E4/E4	E4/E4
3	TCW2E33-3D11	Caucasian	M	77	80	AD (0.5)	E4/E4	E3/E3
4	TCW2E44-4B12	Caucasian	M	77	80	AD (0.5)	E4/E4	E4/E4
5	TCW2E33-2E3	Caucasian	M	77	80	AD (0.5)	E4/E4	E3/E3
6	TCW2E44-4B1	Caucasian	M	77	80	AD (0.5)	E4/E4	E4/E4
7	TCW3E33-H-2	Caucasian	M	80	83	AD (0.5)	E4/E4	E3/E3
8	TCW3E44-F-2	Caucasian	M	80	83	AD (0.5)	E4/E4	E4/E4

The table shows hiPSC name, patient ethnicity, gender, age of AD onset, age at skin biopsy, disease status (CDR at biopsy), original APOE genotype and genetic modification. F female, M male, AD Alzheimer’s disease, APOE apolipoprotein, CDR clinical dementia rating, hiPSC human induced pluripotent stem cells. These cells were previously generated and characterized by [29]

ISSN: 1750-1326