Skip to main content

Table 2 Details of Human Cases. 

From: Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques

Case number Age Gender Aβ phase Braak stage PMI Neuropathological Diagnosis Type of dementia
1 82 M 5 3 72 AD AD
2 81 F 5 5 48 AD, CAA, I AD
3 85 M 5 3 48 AD, CAA, MI AD-VaD
4 83 M 5 5 24 AD, CAA, I, B AD-VaD
5 83 F 4 4 24 p-preAD, AGD, CM 0
6 85 F 4 3 24 p-preAD 0
7 87 M 4 3 96 p-preAD, CAA 0
8 72 M 2 3 72 p-preAD, I 0
9 75 M 1 2 48 p-pre-AD, AGD 0
10 66 F 0 0 48 non-AD control, AGD 0
11 62 M 0 0 48 non-AD control 0
12 64 M 0 0 24 non-AD control 0
  1. The table shows the human subjects studied for histology of astrocytes. Indicated are: the age in years, the gender, the Aβ-MTL phase representing the distribution of Aβ deposits in the subfields of the MTL [43], the stage of neurofibrillary tangle pathology according to Braak and Braak [44] (NFT stage), PMI, neuropathological diagnosis and type of dementia. F female, M male, AD Alzheimer’s disease, AD-VaD Alzheimer’s disease plus signs of vascular dementia, p-preAD preclinical AD, non-AD non-demented control, AGD argyrophilic grain disease, B bleeding, CAA cerebrovascular angiopathy, CM carcinoma metastasis, I infarction, MI microinfraction, PMI post-mortem interval