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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Challenge accepted: uncovering the role of rare genetic variants in Alzheimer’s disease

Fig. 1

Top results (based on Fisher's Exact test p-value) for Confirmed (genes with strong evidence or replication) or Candidate (suggestive role, replication needed) in AD, based on the genes described in this review. Also shown are pathways emerging only with the addition of these Candidate genes (Novel). Gene set analyses were performed using the Gene Ontology website (http://geneontology.org/), analyzing the provided biological processes of the gene set. The X-axis represents the percent of the pathway represented out of total genes possible for that pathway. Y-axis shows gene ontology terms and IDs. The color of the bars indicates the significance level.

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