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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Dynamic changes of CSF sPDGFRβ during ageing and AD progression and associations with CSF ATN biomarkers

Fig. 1

Natural trajectories and evolution sequence of AD core biomarkers and pericyte damage in lifetime. A CSF sPDGFRβ levels were progressively increased with age in CADS cohort (n = 303). B Natural trajectories of AD core biomarkers and sPDGFRβ in CSF. Shading represents 95% CIs. The vertical dashed line at 39.6 years represents the age when CSF Aβ42 began to decline. AD, Alzheimer’s disease; CADS, Chongqing Ageing & Dementia Study; CSF, cerebrospinal fluid; T-tau, total-tau; P-tau, phosphorylated tau; sPDGFRβ, soluble platelet-derived growth factor receptor β

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Molecular Neurodegeneration

ISSN: 1750-1326