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Fig. 11 | Molecular Neurodegeneration

Fig. 11

From: Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and application

Fig. 11

Spatial transcriptomics analysis of an AD mouse model. Data from four 18-month-old mice, including 2 AD (AD.1 and AD.2) and 2 WT (WT.1 and WT.2), were analyzed. A Visualization of the Leiden clustering of the tissue domains in the UMAP space; B Spatial distribution of the tissue domains colored by the cluster id in A; C Clustering of spatially correlated genes; D Spatial pattern of a spatially correlated gene cluster #6 which is upregulated in the AD mice

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