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Fig. 7 | Molecular Neurodegeneration

Fig. 7

From: Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro

Fig. 7

Knockdown of predicted key driver C1qc, but not Prdx1, dampens microglial activation in vitro. Expression of activated microglial genes Lpl, Trem2, Lyz2, Cst7, and Ccl4 following knockdown of (a) C1qc or (b) Prdx1. Expression is presented as fold change, normalized to GAPDH and negative control. n = 3 mice per group, two-tailed paired t test; *, p < 0.05; **, p < 0.01

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Molecular Neurodegeneration

ISSN: 1750-1326