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Fig. 2 | Molecular Neurodegeneration

Fig. 2

From: Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration

Fig. 2

Antemortem CSF SRM intensities of the synaptic panel across patient groups. Violin plots show the distribution of SRM intensities for each synaptic protein quantified in CSF for patients with neuropathological confirmation of FTLD-Tau (Tau), FTLD-TDP (TDP) or AD and cognitively normal subjects (Control). Solid horizontal lines show the mean value for each and boxes represent the standard error of the mean. The horizontal dotted line represents the mean value in the control group for each protein. Summary statistics for ANCOVA including sex and age-at-CSF performed on square root transformed data are shown at the top of each plot. ANCOVA p-values are adjusted for multiple testing (9 proteins). *p < .05, **p < .01 for Dunnet’s post-hoc tests

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Molecular Neurodegeneration

ISSN: 1750-1326