Table 1 17q21.31 H1 sub-haplotype blocks associated with PD susceptibility
Stage 1 | Stage 2 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Block | #Sub-haplotypes | #SNPs | Start | Stop | Gene | Location | p-value | -log10 p-value | FDR p-value | p-value | -log10 p-value | FDR p-value |
H1.1 | 5 | 5 | 44,040,184 | 44,041,992 | MAPT | Intronic | 1.35E-08 | 7.87 | 1.73E-06 | 1.94E-03 | 2.71 | 4.50E-03 |
H1.2 | 8 | 8 | 44,090,196 | 44,097,249 | MAPT | Intronic/Exonic | 6.58E-06 | 5.18 | 2.40E-04 | 1.12E-09 | 5.95 | 7.84E-06 |
H1.3 | 7 | 9 | 44,119,987 | 44,131,305 | KANSL1 | Intronic | 1.23E-07 | 6.91 | 1.05E-05 | 2.39E-04 | 3.47 | 1.12E-03 |