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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: When the infectious environment meets the AD brain

Fig. 1

 Convergence of the amyloid and infectious theories of Alzheimer's Disease. We suggest that deposition of amyloid β causes increased visibility and susceptibility of the CNS to systemic infectious agents and their components coming from the systemic environment. In turn, infectious agents and PAMPs increase AD pathology and cortical neuron death. These result in a vicious cycle that accelerates neurodegeneration

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Molecular Neurodegeneration

ISSN: 1750-1326