Fig. 6From: Common mouse models of tauopathy reflect early but not late human diseaseComparison of the modification landscape of murine and human insoluble Tau. Insoluble Tau of the cortex of P301S and P301L mouse models shows a similar phosphorylation pattern to early stages of human AD and human P301L carriers (human AD data is adapted from [20]). Tau ubiquitination and acetylation of human late-stage AD is not represented in both mouse models. The represented modification sites are documented in table S2. Transverse lines indicate the absence of two N-terminal repeat regions in the human Tau transgene of both mouse models as both models only overexpress 0N4R TauBack to article page