Fig. 4
From: Carriers of the p.P522R variant in PLCγ2 have a slightly more responsive immune system
Response to SARS-CoV-2 vaccination in p.P522R-carriers and non-carriers. Samples were donated 7–14 weeks after second vaccination. Type of vaccine received by donors: Comirnaty® (Pfizer/BioNTech) – 9 carriers, 9 non-carriers; Spikevax® (Moderna)- 1 carrier, 0 non-carriers; Vaxzevria® (AstraZeneca) – 0 carriers, 1 non-carrier; vaccine type not indicated- 0 carriers, 2 non-carriers. One donor reported a confirmed SARS-CoV-2 infection, this donor is indicated with an open grey circle. A Serum IgM, IgA, and IgG response against the Receptor Binding Domain (RBD), spike protein (S-protein) and nucleocapsid protein (N-protein), expressed in IU/mL. B Composition of the serum Ig response per antigen, expressed as % of total antigen-specific Ig response