Volume 7 Supplement 1

Proceedings of the 2011 International Conference on Molecular Neurodegeneration

Meeting abstracts

Edited by Hui Zheng, Bob Vassar, Caroline Stetler and Chunjiu Zhong

2011 International Conference on Molecular Neurodegeneration.

Shanghai, China22-24 September 2011

Concatenated PDF 7S1

Page 1 of 2

Discovery of nitric oxide and cyclic GMP in cell signaling and their role in drug development

Authors: Ferid Murad

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L1

Content type: Lecture presentation Published on: 7 February 2012
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Stringently regulated p23 expression is critical for coordinated movement in mice: implications for Alzheimer’s disease

Authors: Ping Gong, Jelita Roseman, Kulandaivelu S Vetrivel, Vytautas P Bindokas, Lois A Zitzow, Satyabrata Kar, Angèle T Parent and Gopal Thinakaran

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L2

Content type: Lecture presentation Published on: 7 February 2012
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BACE1, the Alzheimer's beta-secretase enzyme, in health and disease

Authors: Robert Vassar

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L3

Content type: Lecture presentation Published on: 7 February 2012
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Gamma-secretase: from pathogenesis to therapeutics

Authors: Yueming Li

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L4

Content type: Lecture presentation Published on: 7 February 2012
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Structure-function relationship of γ-secretase

Authors: Taisuke Tomita

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L5

Content type: Lecture presentation Published on: 7 February 2012
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Sorting out the cell biology of Alzheimer’s disease: focus on BACE1 and APP

Authors: Wim Annaert

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L6

Content type: Lecture presentation Published on: 7 February 2012
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Deciphering the role of APP in synaptic function

Authors: Hui Zheng

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L7

Content type: Lecture presentation Published on: 7 February 2012
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Presenilins in Alzheimer’s disease and frontotemporal dementia

Authors: Jie Shen

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L8

Content type: Lecture presentation Published on: 7 February 2012
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β - but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia

Authors: Robert Tamayev, Shuji Matsuda and Luciano D’Adamio

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L9

Content type: Lecture presentation Published on: 7 February 2012
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ApoE and apoE receptors in brain lipid metabolism and AD

Authors: Guojun Bu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L10

Content type: Lecture presentation Published on: 7 February 2012
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ApoER2 trafficking, processing and signaling and its participation in neurodegeneration

Authors: María-Paz Marzolo

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L11

Content type: Lecture presentation Published on: 7 February 2012
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Elucidating the mechanisms underlying Alzheimer's disease-associated genetic polymorphisms

Authors: Steven Estus

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L12

Content type: Lecture presentation Published on: 7 February 2012
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Molecular pathways to Parkinson’s disease

Authors: Ming Guo

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L13

Content type: Lecture presentation Published on: 7 February 2012
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Does axonopathy play a role in Parkinson's disease?

Authors: Karen L O’Malley, Jo Ann Antenor-Dorsey and Jeong Sook Kim-Han

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L14

Content type: Lecture presentation Published on: 7 February 2012
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Abstract withdrawn

Authors:

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L15

Content type: Lecture presentation Published on: 7 February 2012
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The role of DJ-1 in anti-apoptosis

Authors: Haigang Ren, Kai Fu, Jun Fan and Guanghui Wang

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L16

Content type: Lecture presentation Published on: 7 February 2012
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Neuropathology of transgenic HD animal models

Authors: Xiaojiang Li and Shihua Li

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L17

Content type: Lecture presentation Published on: 7 February 2012
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Novel circuitry and molecular pathogenic mechanisms in Huntington's disease

Authors: X William Yang

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L18

Content type: Lecture presentation Published on: 7 February 2012
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Mechanisms and models of TDP-43 proteinopathies

Authors: Leonard Petrucelli

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L19

Content type: Lecture presentation Published on: 7 February 2012
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Epigenetic gambling & epigenetic drift as potential mechanisms underlying the quasi-stochastic distributions of late life neurodegenerative disorders

Authors: George M Martin

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L20

Content type: Lecture presentation Published on: 7 February 2012
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The roles of fractalkine signaling in neurodegenerative disease

Authors: Bruce Lamb

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L21

Content type: Lecture presentation Published on: 7 February 2012
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Identifying an APP-binding protein in neuronal cell death

Authors: Yunwu Zhang and Huaxi Xu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L22

Content type: Lecture presentation Published on: 7 February 2012
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Reticulon 3 aggregation and its role in the formation of dystrophic neurites

Authors: Riqiang Yan

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L23

Content type: Lecture presentation Published on: 7 February 2012
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Prevention of cognitive deficits in Alzheimer’s mouse model by elevating brain magnesium

Authors: Guosong Liu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L24

Content type: Lecture presentation Published on: 7 February 2012
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Selenite benefits embryonic stem cells therapy in the animal models of Parkinson’s disease through inhibiting inflammation

Authors: Lipeng Tian, Shi Zhang, Liang Xu, Wen Li, Ying Wang, Wei Chen, Jianqing Ding and Shengdi Chen

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L25

Content type: Lecture presentation Published on: 7 February 2012
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Disruption of specific GDNF receptor subtype signaling impairs cortical neuronal survival in Alzheimer’s brains

Authors: Yoshihiro Konishi, Libang Yang, Ping He, Kristina Lindholm, Bai Lu, Rena Li and Yong Shen

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):L26

Content type: Lecture presentation Published on: 7 February 2012
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Aggregation of TDP-43 fragments triggers cellular aberrant function: implication in neurodegeneration

Authors: Meixia Che, Leilei Jiang, Chenjie Zhou, Yajun Jiang and Hongyu Hu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O1

Content type: Oral presentation Published on: 7 February 2012
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Lysosomal function in neurodegenerative diseases

Authors: Jianhua Zhang

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O2

Content type: Oral presentation Published on: 7 February 2012
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Dynamic neuronal regulatory network during the progression of Alzheimer’s disease suggests an adaptive survival strategy

Authors: Jiya Sun, Xuemei Feng, Dapeng Liang, Yong Duan and Hongxing Lei

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O3

Content type: Oral presentation Published on: 7 February 2012
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Molecular mechanisms for simvastatin-mediated enhancement of synaptic plasticity

Authors: Robert A Mans, Lori L McMahon and Ling Li

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O4

Content type: Oral presentation Published on: 7 February 2012
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Wnt signaling receptor LRP6 interacts with amyloid precursor protein and regulates its trafficking and processing

Authors: Chia-Chen Liu, Hyang-Sook Hoe and Guojun Bu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O5

Content type: Oral presentation Published on: 7 February 2012
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Chronic cerebral hypoperfusion induces UCP2 expression by decreasing mitochondrial respiratory activities in aging rat brain

Authors: Minna Gao, Li Liu, Linhui Wang, Gang Yu and Yu Li

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O6

Content type: Oral presentation Published on: 7 February 2012
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Upregulation of astrocytic α7 nicotinic receptors in Alzheimer's disease brain- possible relevant to amyloid pathology

Authors: Wenfeng Yu, Naguib Mechawar, Slavica Krantic, Jean-Guy Chabot and Rémi Quirion

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O7

Content type: Oral presentation Published on: 7 February 2012
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Application of bimolecular fluorescence complementation in studying the topology of polytopic proteins

Authors: Xingya Chang and Fei Dou

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O8

Content type: Oral presentation Published on: 7 February 2012
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Implication of lipid metabolism disturbance and Alzheimer’s disease: focus on the lipoprotein lipase plays an important role in learning and memory function

Authors: Dehua Chui, Ting Zhou, Liang Zhou, Huan Yang, Xinying Liu, Tingting Liu, Jia Yu, Yi Liu, Xue Fei Wu, Hui Zhang and Dongsheng Fan

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O9

Content type: Oral presentation Published on: 7 February 2012
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Formononetin could increase soluble-APPα secretion by up-regulating ADAM10 level

Authors: Ting Zhou, Miao Shun, Liang Zhou, Huan Yang, Kaiyin Zhong, Ximeng Zhang, Hui Zhang, Dongsheng Fan and Dehua Chui

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O10

Content type: Oral presentation Published on: 7 February 2012
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DnaJB6: an indirect interaction protein of 15-kDa selenoprotein

Authors: Jing Tian, Qiong Liu and Jiazuan Ni

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O11

Content type: Oral presentation Published on: 7 February 2012
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EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation

Authors: Ying Yang, Xiaogang Shu, Dan Liu, Lei Pei, Lingqiang Zhu, Qing Tian, Jianzhi Wang and Youming Lu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O12

Content type: Oral presentation Published on: 7 February 2012
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A tet-on system for Drd1a-expressing cells

Authors: Fayi Yao and Robert G MacKenzie

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O13

Content type: Oral presentation Published on: 7 February 2012
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Beneficial effects of tri-lithium pyrroloquinoline quinonein on behaviors and pathology in a mouse model of Alzheimer’s disease

Authors: Lei Zhao, Neng Gong, Xiaojing Sun, Zhe Yu, Qi Fang, Na Zhao, Xiaoli Pan, Tianle Xu and Chunjiu Zhong

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):O14

Content type: Oral presentation Published on: 7 February 2012
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Chronic cerebral hypoperfusion induces ABCA1 and apolipoprotein A I mediated cellular cholesterol efflux by activating LXR/RXR in aging rat brain

Authors: Linhui Wang, Mingyuan Tian, Li Tang, Bin Liu and Yu Li

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S1

Content type: Meeting abstract Published on: 7 February 2012
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Neuroprotective efficacy of ABCA1 and HDL in aging rats with cerebrovascular hypoperfusion

Authors: Linhui Wang, Mingyuan Tian, Gang Yu, Hongchi Luo and Yu Li

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S2

Content type: Meeting abstract Published on: 7 February 2012
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Curcumin preserves cognitive function and improve serum HDL in chronic cerebral hypoperfusion aging-rats

Authors: Mingyuan Tian, Linhui Wang, Gang Yu, Bin Liu and Yu Li

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S3

Content type: Meeting abstract Published on: 7 February 2012
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Effects of an early- and late-stage treatment with Geniposide on cognitive dysfunction in a transgenic mouse model relevant to Alzheimer's disease

Authors: Lei Wang, Shijun Yan and Wensheng Zhang

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S4

Content type: Meeting abstract Published on: 7 February 2012
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Puromycin-sensitive aminopeptidase is involved in wild-type huntingtin clearance

Authors: Guijie Ren, Zonghcai Ma, Maria Hui, Lili C Kudo, Koon-Sea Hui and Stanislav L Karsten

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S5

Content type: Meeting abstract Published on: 7 February 2012
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The role of ATP-sensitive potassium channels on DMT1-mediated ferrous iron uptake in SK-N-SH cells

Authors: Xixun Du, Huamin Xu, Ning Song, Hong Jiang and Junxia Xie

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S6

Content type: Meeting abstract Published on: 7 February 2012
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Curcumin promotes cholesterol efflux from brain through LXR/RXR-ABCA1-apoA1 pathway in chronic cerebral hypoperfusion aging-rats

Authors: Mingyuan Tian, Linhui Wang, Gang Yu, Bin Liu and Yu Li

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S7

Content type: Meeting abstract Published on: 7 February 2012
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The protective effects of TanIIA on neurotoxicity induced by β-amyloid protein through the Cdk5/P35 pathway in cultured primary neurons

Authors: Lili Shi, Weina Yang, Yihua Qian, Jianshui Zhang, Xinlin Chen and Yong Liu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S8

Content type: Meeting abstract Published on: 7 February 2012
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The study of the association of the p35 rs17852832 SNP polymorphism with Alzheimer’s disease

Authors: Lili Shi, Yihua Qian, Xiaodan Hu, Hua Han and Yong Liu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S9

Content type: Meeting abstract Published on: 7 February 2012
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Curcumin protects brain from oxidative stress through inducing expression of UCP2 in chronic cerebral hypoperfusion aging-rats

Authors: Li Liu, Peng Zhang, Yu Li and Gang Yu

Citation: Molecular Neurodegeneration 2012 7(Suppl 1):S10

Content type: Meeting abstract Published on: 7 February 2012
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Proceedings of the 2011 International Conference on Molecular Neurodegeneration

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