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Aneuploidy-driven non-heritable genomic variations demonstrate area-specific distribution in the Alzheimer’s disease brain

Authors: Ivan lourov, Svetlana Vorsanova, Thomas Liehr and Yuri Yurov

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P52

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Mechanism of tau transfer: insights from cell culture and animal models

Authors: Jessica Wu, Dara Dickstein and Karen Duff

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P50

Content type: Poster presentation Published on: 13 September 2013

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Differential pathways for the interleukin-1β production activated by chromogranin A and Aβ in microglia

Authors: Zhou Wu and Hiroshi Nakanishi

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P48

Content type: Poster presentation Published on: 13 September 2013

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Phosphorylation of hnRNP K controls cytosolic accumulation of TDP-43

Authors: Anthony White, Diane Moujalled, Janine James, Alexandra Grubman, Katja Kanninen and Peter Crouch

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P46

Content type: Poster presentation Published on: 13 September 2013

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Role of ROS in Aβ42 mediated cell surface P-selectin expression and actin polymerization

Authors: Andrey Tsoy, Sholpan Askarova, Tamara Shalakhmetova, Bauyrzhan Umbayev, Shalkar Adambekov and Zhaksybay Zhumadilov

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P44

Content type: Poster presentation Published on: 13 September 2013

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Exposure to the saturated free fatty acid palmitate alters microglia inflammatory response

Authors: Linda Tracy, Filip Bergqvist, Elena Ivanova, Kristin Jacobsen and Kerstin Iverfeldt

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P42

Content type: Poster presentation Published on: 13 September 2013

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Bexarotene treatment does not clear β-Amyloid in an AD mouse model and Beagle dogs

Authors: Ina Tesseur, Adrian Lo, Anouk Roberfroid, Sofie Dietvorst, Bianca Van Broeck, Marianne Borgers, Harrie Gijsen, Diederik Moechars, Marc Mercken, John Kemp, Rudi D’Hooge and Bart De Strooper

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P40

Content type: Poster presentation Published on: 13 September 2013

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Neuronal MHC-I display in T-cell mediated neurodegeneration

Authors: Carolina Cebrián, Fabio Zucca, Luigi Zecca, John Loike and David Sulzer

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P38

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Harnessing endogenous pathways and metabolites to treat or prevent neurodegenerative disease

Authors: Todd E Golde, Kevin Felsenstein, Paramita Chakrabarty, Andy Li, Brenda Moore, Jung Joo In, Pedor Cruz, Ashely Price, David Borchelt, Christopher Janus, Carolina Cebballos-Diaz and Awilda Rosario

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O36

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Identification of proteins potentially involved in the formation of Lafora bodies, a hallmark of Lafora disease

Authors: Elham Schokraie, Oliver Kötting and Matthew S Gentry

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P36

Content type: Poster presentation Published on: 13 September 2013

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Excitotoxicity increases the release of 24S-hydroxycholesterol via CYP46A1 activation

Authors: Alejandro Sodero, Joris Vriens, Debapriya Ghosh, David Stegner, Anna Brachet, Marta Pallotto, Marco Sassoe-Pognetto, Jos Brouwers, Bernd Helms, Bernard Nieswandt, Thomas Voets and Carlos Dotti

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O32

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Peripheral inflammation increases PKR activation, Tau phosphorylation and amyloid β production in wild-type mice

Authors: François Mouton-Liger, Anne-Sophie Rebillat, Clarisse Pace, Sarah Gourmaud, Mariko Taga, Claire Paquet and Jacques Hugon

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P32

Content type: Poster presentation Published on: 13 September 2013

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Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of AD

Authors: Stephanie Fowler, Angie Chiang, Ricky Savjani, Megan Larson, Dorothy Schuler, John Cirrito, Sylvain Lesne and Joanna Jankowsky

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O30

Content type: Oral presentation Published on: 13 September 2013

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Glutathion-S-Transferases (GSTs) and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model

Authors: Elcin Deniz Ozdamar and Benay Can-Eke

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P30

Content type: Poster presentation Published on: 13 September 2013

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Identification of potent inhibitors of microtubule affinity regulating kinase for inhibition of tau hyperphosphorylation

Authors: Alison Levy, Michelle Newman, Janet Brownlees, Denise Harding, Joanne Osborne, Stephen Lewis, Kevin Gillen, Gareth Hall, Chido Mpamhanga, Andy Merritt, Debra Taylor and Ed Mclver

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P28

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Mechanisms of Aβ induced synaptic toxicity

Authors: Edward H Koo

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O26

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Cytoprotective functions of amyloid precursor protein family members in stress signaling and aging

Authors: Arpita Kundu, Andreas Zymny, Steffi Chang, Nelli Röhner and Donat Kögel

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P26

Content type: Poster presentation Published on: 13 September 2013

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The transcription factor XBP-1 in neurodegenerative diseases

Authors: Frédéric Checler, Eric Duplan and Cristine Alves da Costa

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O24

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Regulation of Fe65 during neuronal differentiation

Authors: Niina Koistinen, Kristin Jacobsen and Kerstin Iverfeldt

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P24

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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A novel mechanism underlying pathogenesis of Down syndrome

Authors: Xin Wang, Yingjun Zhao, Xiaofei Zhang, Ying Zhou, Barbara Ranscht, Fred H Gage, William C Mobley, Yun-wu Zhang, Stuart A Lipton, Wanjin Hong and Huaxi Xu

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O23

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Secretases: potential and roadblocks on the way to therapy

Authors: Bart De Strooper

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O22

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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FcgRIIb mediates amyloid-β neurotoxicity and memory impairment in a model of Alzheimer’s disease

Authors: Yong-Keun Jung

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P22

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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O-GlcNAcylation increases non-amyloidogenic processing of the amyloid-β precursor protein (APP)

Authors: Kristin Jacobsen and Kerstin Iverfeldt

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P21

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Vascular hypothesis of Alzheimer’s disease: role of apoE and apoE receptors

Authors: Guojun Bu, Chia-Chen Liu and Takahisa Kanekiyo

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O20

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1

Authors: Mari Takalo, Jayashree Viswanathan, Teemu Natunen, Kaisa MA Kurkinen, Heikki Tanila, Hilkka Soininen, Rudolph E Tanzi, Mikko Hiltunen and Annakaisa Haapasalo

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P20

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Super-resolution fluorescence imaging of intracellular mutant huntingtin protein reveals a population of fibrillar aggregates co-existing with compact perinuclear inclusion bodies

Authors: Steffen J Sahl, Lucien E Weiss, Lana Lau, Judith Frydman and WE Moerner

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O18

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Serum from Parkinson’s disease patients presents excess of protein halogenation and nitrosylation, with anomalous nitrosylation of serum α-synuclein as potentially etiological factor

Authors: Emilio Fernandez, Jose-Manuel Garcia-Moreno, Angel Martin de Pablos and Jose Chacon

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P18

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Novel non-carbohydrate O-GlcNAcase inhibitors with CNS drug properties as potential treatment for Alzheimer’s disease and tauopathies

Authors: Heike Hering, Danielle Graham, Solenne Ousson, Maud Neny, Audrey Gray, Brandy Giacomozzi, John Joyce, Vikram Dutt, Michael Busch, Andrew Cameron, Leslie Liu-Bujalski, Henry Yu, Hui Tian, Mark Shearman, Anna Quattropani, Bruno Permanne…

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O17

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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A cell-based model of pathological tau uptake and propagation

Authors: Ben Falcon, Rachel Angers and Michel Goedert

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P17

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Designing nanoparticles for delivery of neurotrophic proteins

Authors: Angelina Angelova, Borislav Angelov and Sylviane Lesieur

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O16

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Altered expression of antioxidant enzymes and autophagic proteins in transglutaminase 2 knockout mice

Authors: Barbara D’Orio, Luana Barone, Anna Fracassi, Francesca Fanelli, Sara Sepe, Marco Segatto, Mauro Piacentini, Roberta Nardacci and Sandra Moreno

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P15

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Expanded G4C2 repeats linked to C9ORF72ALS and FTD form length-dependent RNA foci, sequester RNA binding proteins and are neurotoxic

Authors: Youn-Bok Lee, Han-Jou Chen, João N Peres, Jorge Gomez, Valentina Sardone, Agnes L Nishimura, Emma Scotter, Caroline Vance, Maja Štalekar, Yoshitsugu Adachi, Claire Troakes, Jack Miller, Bradley Smith, Frank Hirth, Boris Rogelj, Corinne Houart…

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O14

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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The dishomeostasis of metal ions plays an important role for the cognitive impartment

Authors: Dehua Chui, Huan Yang, Hecheng Wang, Tuo JI, Jia Yu, Shouzi Zhang, Zheng Chen and WeiZhong Xiao

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P13

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Genetic analysis of neurodegeneration.. the end game

Authors: John Hardy

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O12

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Function and dysfunction of presenilin in Alzheimer’s disease

Authors: Jie Shen

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O11

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Posterior cortical atrophy: correlation between clinical, neuropsychological, magnetic resonance and positron emission tomography Imaging

Authors: Tinatin Chabrashvili, Haley Lamonica and Bassel Sawaya

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P11

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model

Authors: Rahman Basaran, Elcin Deniz Ozdamar and Benay Can-Eke

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P9

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Neurochemical changes in animal models of Parkinson’s disease

Authors: Mária Baranyi, Elisaveta Milusheva and Beáta Sperlágh

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P7

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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BACE1, the Alzheimer’s beta-secretase enzyme, in health and disease

Authors: Robert Vassar

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O7

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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RAGE targeted strategies for Alzheimer’s amyloid β peptide induced blood brain barrier dysfunctions

Authors: Sholpan Askarova, Andrey Tsoy and James C-M Lee

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P5

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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The biological function of β-secretase

Authors: Christian Haass

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O5

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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dld-1 suppression attenuates the detrimental effects of amyloid beta deposition in a Caenorhabditis elegansmodel of Alzheimer’s disease

Authors: Waqar Ahmad and Paul Ebert

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P3

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Functional genetics – an approach to mechanisms in Alzheimer’s disease

Authors: Mikko Hiltunen

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):O3

Content type: Oral presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Methylene blue decreases brain mitochondrial ABAD and amyloid beta levels protecting mitochondrial functions in LPS-mouse model

Authors: Reham M Abdel-Kader, Aya Zakaria and Nabila Hamdi

Citation: Molecular Neurodegeneration 2013 8(Suppl 1):P1

Content type: Poster presentation Published on: 13 September 2013

This article is part of a Supplement: Volume 8 Supplement 1
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Rapamycin increases survival in ALS mice lacking mature lymphocytes

Amyotrophic Lateral Sclerosis (ALS) is a devastating progressive neurodegenerative disease. Disease pathophysiology is complex and not yet fully understood, but is proposed to include the accumulation of misfo...

Authors: Kim A Staats, Sara Hernandez, Susann Schönefeldt, André Bento-Abreu, James Dooley, Philip Van Damme, Adrian Liston, Wim Robberecht and Ludo Van Den Bosch

Citation: Molecular Neurodegeneration 2013 8:31

Content type: Short report Published on: 11 September 2013
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Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

Amyotrophic lateral sclerosis (ALS)-linked fused in sarcoma/translocated in liposarcoma (FUS/TLS or FUS) is concentrated within cytoplasmic stress granules under conditions of induced stress. Since only the mu...

Authors: Desiree M Baron, Laura J Kaushansky, Catherine L Ward, Reddy Ranjith K Sama, Ru-Ju Chian, Kristin J Boggio, Alexandre J C Quaresma, Jeffrey A Nickerson and Daryl A Bosco

Citation: Molecular Neurodegeneration 2013 8:30

Content type: Research article Published on: 31 August 2013
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S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson’s disease

Mutations in the gene encoding parkin, a neuroprotective protein with dual functions as an E3 ubiquitin ligase and transcriptional repressor of p53, are linked to familial forms of Parkinson’s disease (PD). We...

Authors: Carmen R Sunico, Tomohiro Nakamura, Edward Rockenstein, Michael Mante, Anthony Adame, Shing Fai Chan, Traci Fang Newmeyer, Eliezer Masliah, Nobuki Nakanishi and Stuart A Lipton

Citation: Molecular Neurodegeneration 2013 8:29

Content type: Research article Published on: 28 August 2013
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Genetics of amyotrophic lateral sclerosis: an update

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder involving both upper motor neurons (UMN) and lower motor neurons (LMN). Enormous research has been done in the past few decades i...

Authors: Sheng Chen, Pavani Sayana, Xiaojie Zhang and Weidong Le

Citation: Molecular Neurodegeneration 2013 8:28

Content type: Review Published on: 13 August 2013
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Autophagy is involved in oligodendroglial precursor-mediated clearance of amyloid peptide

Accumulation of β-amyloid peptides is an important hallmark of Alzheimer’s disease (AD). Tremendous efforts have been directed to elucidate the mechanisms of β-amyloid peptides degradation and develop strategi...

Authors: Wenxia Li, Yifen Tang, Zhiqin Fan, Ya Meng, Guang Yang, Jia Luo and Zun-Ji Ke

Citation: Molecular Neurodegeneration 2013 8:27

Content type: Research article Published on: 10 August 2013
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Erratum to: treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice

Authors: Katherine D LaClair, Kebreten F Manaye, Dexter L Lee, Joanne S Allard, Alena V Savonenko, Juan C Troncoso and Philip C Wong

Citation: Molecular Neurodegeneration 2013 8:26

Content type: Erratum Published on: 8 August 2013

The original article was published in Molecular Neurodegeneration 2013 8:18
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