%PDF-1.3
%
1 0 obj
<>
endobj
2 0 obj
<>stream
Cerebrospinal fluid,Neurofilament medium polypeptide (NEFM),Neuronal pentraxin 2 (NPTX2),Neurosecretory protein VGF (VGF),Aquaporin 4 (AQP4),LASSO,Random forest,Suspension bead array
Acrobat Distiller 10.0.0 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
application/pdf
10.1186/s13024-021-00499-4
Molecular Neurodegeneration
Molecular Neurodegeneration, 2021, doi:10.1186/s13024-021-00499-4
Cerebrospinal fluid
Neurofilament medium polypeptide (NEFM)
Neuronal pentraxin 2 (NPTX2)
Neurosecretory protein VGF (VGF)
Aquaporin 4 (AQP4)
LASSO
Random forest
Suspension bead array
A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study
Sofia Bergström
Linn Öijerstedt
Julia Remnestål
Jennie Olofsson
Abbe Ullgren
Harro Seelaar
John C. Swieten
Matthis Synofzik
Raquel Sanchez-Valle
Fermin Moreno
Elizabeth Finger
Mario Masellis
Carmela Tartaglia
Rik Vandenberghe
Robert Laforce
Daniela Galimberti
Barbara Borroni
Chris R. Butler
Alexander Gerhard
Simon Ducharme
Jonathan D. Rohrer
Anna Månberg
Caroline Graff
Peter Nilsson
2021-11-27T09:09:15+01:00
2021-11-27T09:09:15+01:00
2021-11-22T12:18:43+08:00
Arbortext Advanced Print Publisher 9.1.440/W Unicode
uuid:f45a65e0-4621-4e5a-8acf-68e463216bec
uuid:562045ab-3fff-48d3-acb3-5aadae764389
default
1
converted
uuid:f45a65e0-4621-4e5a-8acf-68e463216bec
converted to PDF/A-2b
pdfToolbox
2021-11-24T02:17:55+08:00
2
B
Sofia Bergström
http://orcid.org/0000-0003-2910-4754
Springer Nature ORCID Schema
http://springernature.com/ns/xmpExtensions/2.0/
sn
authorInfo
Bag AuthorInformation
external
Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.
editorInfo
Bag EditorInformation
external
Editor information: contains the name of each editor and his/her ORCID identifier.
seriesEditorInfo
Bag SeriesEditorInformation
external
Series editor information: contains the name of each series editor and his/her ORCID identifier.
AuthorInformation
http://springernature.com/ns/xmpExtensions/2.0/authorInfo/
author
Specifies the types of author information: name and ORCID of an author.
name
Text
Gives the name of an author.
orcid
URI
Gives the ORCID of an author.
EditorInformation
http://springernature.com/ns/xmpExtensions/2.0/editorInfo/
editor
Specifies the types of editor information: name and ORCID of an editor.
name
Text
Gives the name of an editor.
orcid
URI
Gives the ORCID of an editor.
SeriesEditorInformation
http://springernature.com/ns/xmpExtensions/2.0/seriesEditorInfo/
seriesEditor
Specifies the types of series editor information: name and ORCID of a series editor.
name
Text
Gives the name of a series editor.
orcid
URI
Gives the ORCID of a series editor.
http://ns.adobe.com/pdf/1.3/
pdf
Adobe PDF Schema
internal
A name object indicating whether the document has been modified to include trapping information
Trapped
Text
http://ns.adobe.com/xap/1.0/mm/
xmpMM
XMP Media Management Schema
internal
UUID based identifier for specific incarnation of a document
InstanceID
URI
internal
The common identifier for all versions and renditions of a document.
OriginalDocumentID
URI
internal
A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original.
DerivedFrom
ResourceRef
Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced.
http://ns.adobe.com/xap/1.0/sType/Part#
stPart
Part
http://ns.adobe.com/xap/1.0/t/pg/
xmpTPg
XMP Paged-Text
internal
A structure containing the characteristics of a font used in a document
Fonts
Bag Font
internal
XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents).
PlateNames
Seq Text
A structure containing the characteristics of a font used in a document.
http://ns.adobe.com/xap/1.0/sType/Font#
stFnt
Font
http://ns.adobe.com/pdfx/1.3/
pdfx
Adobe Document Info PDF eXtension Schema
internal
ID of PDF/X standard
GTS_PDFXVersion
Text
internal
Conformance level of PDF/X standard
GTS_PDFXConformance
Text
internal
Company creating the PDF
Company
Text
internal
Date when document was last modified
SourceModified
Text
http://www.aiim.org/pdfa/ns/id/
pdfaid
PDF/A ID Schema
internal
Part of PDF/A standard
part
Integer
internal
Amendment of PDF/A standard
amd
Text
internal
Conformance level of PDF/A standard
conformance
Text
endstream
endobj
3 0 obj
<>
endobj
4 0 obj
<>
endobj
6 0 obj
<>
endobj
9 0 obj
<>/BBox[0 0 123.307 7.48401]/Length 15>>stream
HR(T0 u
endstream
endobj
10 0 obj
<>/BBox[0 0 4.933 9.80798]/Length 15>>stream
HR(T0 u
endstream
endobj
11 0 obj
<>/ExtGState<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI]/Font<>>>/Annots[25 0 R 26 0 R 27 0 R 28 0 R 29 0 R 30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R 36 0 R 37 0 R 38 0 R 39 0 R]/CropBox[0 0 595.276 790.866]/Parent 40 0 R/Rotate 0/MediaBox[0 0 595.276 790.866]>>
endobj
12 0 obj
<>stream
x|Ks#ɑ板5g t+ӡZ%]]RѴc6Շ$$s@B@1{^ l[&23?"q?̜g?sY^*fEWg}jyyߞ}~Y6ˬ:yW=k)>xS_,s~|oiR0βP:֗vfͬpTז%=y[WЧ`=1߀ofV9COe{jK=ZO=5QU/ܬtxiF=zs2<]1M
x.
F$+u!DOu2#N=LiPi0:)O~ܸ<=&C-ç#RNx٧?>;{F,YF7C(*p4ϟе!v]sSd'NkzW^8R>2OK!ZSJS-GϏ o=ΧvhILK\2TlL*"*܌aZ{W:4%OP% BX
7Rwyʬrjuz
m/WFLV؏b2OdRbry1UI{7xhPڠn1iz͂cY6}mwvrnq{.wv-mHTVdJ.~vxR盺Mۯondr eDFծvA`sVx:Rĕ,Kgԃrf&5ĩLDbZJ
Roz.'Eaѣe&qYlZ!K$
%>UBMͶ[QsjxȪz!cAv4$9AmaU>zYW`a[M\Gߌo4Ya ٓ`So
=Yv\6ʖU3!l$&ͺnm&~)ᨁ;Mڊ(
__Qf̋RBV56:Kr..ǤzڷzEڭE+YZf!D/(dbk_&/6E&꣯kfcYJ|v"+
qiHvh}ʮp?~ -=?v<ݏeԗɻ~n}xx]Hl/y?ʠ"Y*AլIN<dӆ@A;Z}=vЧ&mF135Dd-IJFpۉvfEtT.z@F|rW$+R\Dh7x y$
EG+
#~+'s h:+sew >â+I1AÆtAmeP?IZ @KrDӣj*Fyb/LUX"N
!_
gKҗ!F5]%d%# !Wt'3OM@\ZGڻ8_@OV"'~/P/ani}3ݳ
2&LK]w5T6~7gjFV!&lǧ#T~rQ4wiUh<'ho`nw.x7v%#vlGH"^`U5 ld"~w!~Ąĩ<VU+|euKUEN26"+x5턥*BATv-{a'hSj`1E wf`1wiǗ9SbB8Z2ա@4VUO
,sk狎c/H*).x? eECƜ$J"OVQaJ%
iy9}gSww(N
gǞ$Twʶo!t,O?pfْvܷHrB8n[5~^cOӝJOEq
!N),@8#SА*1DKh(dCB³%|NںCJw3?L~APMle&aB(yy:o3۳?F@@6r`Z:w-T=xR!G츽0?LI("BSG1yECX6_
ּ;}(,IpQ^TYcE29w̲"A}`_>ja!qTnba:~KfX籫S#b~8M`^zZ+\
;omT/Tf,s;rthb=qx|zXBx_e3Q?[P7[hO49#M@asNT>8j.&M{yں<DQ⛶w1ưGYcGtyRbvڂVс5_C~'fœz BPЙͻr .R7>3`3efA@.vaYqP|}ſ`v/=h_AHE7cHfpьe2$/IgJ륕wc^$a!ծn
V fC@cu?C% jbL
W MP?0 C@+E+E^51G]W"o/8FBwScF>s
-گ-Eqg]La
:jh3׀:%Z"TY`/d|G
Ŀ415L!XZO@~e&5O6(yߢp
Ib텙=Ս=aM=QN֢va˙@N[s_yP`"@ęy]^TD%r3D0tmE5bU2F.?ka#~EC__
A;A^|\`4hZtVF!mI=3;4X[ڢk'Q̄i.Wqlg Fhԩw0D|$r 6I$LW0
"MhÎݾYZ~EހǬ#Ij3M=g__ejXLcXW?|",B/fdtn;Tb
GJNj$=~]F<}L縌Ly˨ \M;
Rsvsl@l&Yb