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Figure 1 | Molecular Neurodegeneration

Figure 1

From: The amyloid precursor protein: beyond amyloid

Figure 1

Amino acid sequence alignment of C. elegans APL-1, Drosophila APPL and human APP, APLP1 and APLP2. Identical sequences are shaded in green and conserved changes in light blue. The E1 and E2 domains are shown in purple and orange underlines respectively. Yellow bracket denotes the transmembrane domain, the Aβ sequences is outlined within the red bracket, and the Thr668 residue and the YENPTY sequence are marked by the asterisk and filled squares underneath the sequences respectively.

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