Figure 8
From: Tau phosphorylation by GSK-3β promotes tangle-like filament morphology
Effects of ThS on filament formation. Polymerization reactions were carried out with 2 μM non-phosphorylated tau under standard conditions with low (25 μM) or optimal (75 μM) ARA inducer:tau ratios without (white bars) or with (black bars) ThS. Error bars represent the SEM. Panel A is a comparison of the number of filaments; Panel B is a comparison of average length of filaments; and Panel C is the calculation of filament "mass" (detailed in Materials and Methods).