Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

Table 1 Differentially expressed miRNAs in the brain of BSE-infected macaques and their relative abundance in the basis pontis region of macaque brain

Regulated miRNAs identified by microarray	relative abundance in macaque brain [% of highest expressed miRNA]	regulation factor
	microarray	stem-loop qRT-PCR	Poly(A)-tailed qRT-PCR
hsa-miR-26a	83,4	3.0 **	1.0
hsa-miR-30a-5p	1,2
hsa-miR-30d	10,6
hsa-miR-103	27,1
hsa-miR-106b	9,0
hsa-miR-107	41,3
hsa-miR-124a	58,4	2.2
hsa-miR-125a	23,6
hsa-miR-128a	22,8
hsa-miR-132	11,3
hsa-miR-143	8,2	0.5
hsa-miR-145	13,9	0.6
hsa-miR-181a	26,3
hsa-miR-191	13,9
hsa-miR-195	4,9
hsa-miR-219	1,3
hsa-miR-320	6,9
hsa-miR-342-3p	8,0	2.7 ***	1.13 ***
hsa-miR-361	8,7
hsa-miR-490	3,6
hsa-miR-494	2,1	3.7 ***	8.1 ***

ISSN: 1750-1326