Figure 3
From: Development of monoclonal antibodies and quantitative ELISAs targeting insulin-degrading enzyme
Immunofluorescent and immunohistochemical detection of IDE in normal human brain tissue. A, B, Hippocampal sections of paraffin-embedded human brain tissue stained with 6H9 (100 μg/mL) and detected by immunofluorescence (A) and immunohistochemistry (B). Note the presence of IDE in pyramidal neurons and glia detected by both methods. C, D, Cerebellar sections stained with 6H9 (100 μg/mL) and detected by immunofluorescence (C) and immunohistochemistry (D). Note the presence of IDE in the cell bodies of Purkinje cells.