| LFD | LFD+NDEA | HFD | HFD+NDEA | F-Ratio | P-Value |
---|---|---|---|---|---|---|
Insulin | 0.093 ± 0.011 | 0.155* ± 0.015 | 0.181** ± 0.028 | 0.069 ± 0.008 | 9.1450 | < 0.0001 |
IGF-1 | 0.170 ± 0.012 | 0.253** ± 0.029 | 0.101* ± 0.015 | 0.101* ± 0.007 | 16.4000 | < 0.0001 |
IGF-2 | 2.336 ± 0.285 | 2.414 ± 0.675 | 1.718 ± 0.219 | 2.004 ± 0.179 | 19.3400 | < 0.0001 |
Insulin R | 1.060 ± 0.129 | 0.977 ± 0.070 | 0.997 ± 0.117 | 0.634* ± 0.073 | 3.6360 | 0.0210 |
IGF-1R | 0.814 ± 0.111 | 1.027 ± 0.098 | 0.482* ± 0.047 | 0.485* ± 0.059 | 10.3700 | < 0.0001 |
IGF-2R | 0.649 ± 0.049 | 0.721 ± 0.107 | 0.893* ± 0.051 | 0.540 ± 0.053 | 4.5660 | 0.0080 |
IRS-1 | 0.393 ± 0.031 | 0.439 ± 0.040 | 0.244** ± 0.013 | 0.185*** ± 0.016 | 19.3400 | < 0.0001 |
IRS-2 | 1.678 ± 0.211 | 2.652 ± 0.406 | 1.127 ± 0.104 | 1.300 ± 0.166 |  |  |
IRS-4 | 0.029 ± 0.005 | 0.153*** ± 0.030 | 0.049 ± 0.007 | 0.025 ± 0.004 | 15.0000 | < 0.0001 |