From: Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated
Parameters of APP-GFP/Cat D co-localization
APP-GFP
% Vesicular co-loc.
% Co-loc. coefficient
Wt
5.0 ± 0.5
6.4 ± 0.7
S655A
9.6 ± 0.4***/+++
10.2 ± 0.8***/+++
S655E
3.1 ± 0.3+++
3.6 ± 0.0*/+++