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Figure 4 | Molecular Neurodegeneration

Figure 4

From: Protein kinase C and rho activated coiled coil protein kinase 2 (ROCK2) modulate Alzheimer's APP metabolism and phosphorylation of the Vps10-domain protein, SorL1

Figure 4

SorL1 interacts with ROCK2. A. Endogenous SorL1 was immunoprecipitated from Wt MEFs using α SorL1 antibody (BD biosciences) or control IgG. Immunooprecipitates were subjected to SDS-PAGE, transferred to PVDF membranes and probed α-ROCK2. ROCK2 was detected in the α-SorL1 precipitate. B. Immunoprecipitation of ROCK2 using α-ROCK2 antibody (BD biosciences) resulted in co-immunoprecipitation of SorL1.

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Molecular Neurodegeneration

ISSN: 1750-1326