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Figure 3 | Molecular Neurodegeneration

Figure 3

From: Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

Figure 3

Immunohistochemical analysis of p23 expression. Sagittal brain sections of Hup23 Tg mice and Ntg littermates were stained with p23 antibody [14]. Shown are pairs of images from transgenic mouse brain (Hup23) and Ntg littermate corresponding to cortex, hippocampus, CA1 region of the hippocampus (CA1), thalamus (Th), deep cerebellar nuclei (DCN), cerebellum (Cb), and pontine nuclei (PN). p23 localizes to the cell body and vertically oriented apical dendrites in Hup23 cortex (Cx). The following areas are indicated: DG, dentate gyrus; gcl, granule cell layer; H, hilus; ml, molecular layer; Pcl, Purkinje cell layer; so, stratum oriens; sp, stratum pyramidale; sr, stratum radiatum; Sb, subiculum.

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