Table 1 Subject characteristics
From: Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts
Cohort | AD cases | Controls (N) | ||||
|---|---|---|---|---|---|---|
N | Age at onset | APOEε2/ε3/ε4 | N | Age at exam | APOEε2/ε3/ε4 | |
(mean ± SD) | (allele %) | (mean ± SD) | (allele %) | |||
ACT | 566 | 83.90 (4.8) | 0.05 / 0.69 / 0.26 | 1696 | 81.08 (6.0) | 0.08 / 0.81 /0.11 |
ADC1 | 1566 | 72.47 (7.1) | 0.03 / 0.55 / 0.42 | 515 | 75.00 (8.0) | 0.08 / 0.76 / 0.16 |
ADC2 | 738 | 73.19 (7.1) | 0.03 / 0.57 / 0.39 | 160 | 75.68 (7.9) | 0.09 / 0.75 / 0.16 |
ADNI | 268 | 75.30 (7.2) | 0.03 / 0.55 / 0.42 | 173 | 78.6 (5.5) | 0.08 / 0.79 / 0.14 |
GenADA | 669 | 74.59 (6.2) | 0.04 / 0.58 / 0.38 | 713 | 74.21 (7.0) | 0.08 / 0.79 / 0.13 |
MIAMI | 1186 | 74.06 (7.8) | 0.03 / 0.61 / 0.36 | 1135 | 74.00 (8.3) | 0.08 / 0.80 / 0.12 |
MIRAGE | 509 | 71.16 (6.5) | 0.04 / 0.60 / 0.36 | 753 | 72.04 (7.2) | 0.06 / 0.72 / 0.23 |
NIA-LOAD | 1811 | 73.57 (6.7) | 0.02 / 0.51 / 0.46 | 1575 | 73.99 (8.5) | 0.07 / 0.73 / 0.20 |
OHSU | 132 | 86.10 (5.5) | 0.07 / 0.70 / 0.23 | 153 | 83.86 (7.6) | 0.10 / 0.82 / 0.08 |
TGEN | 864 | 74.91 (7.2) | 0.04 / 0.57 / 0.40 | 493 | 80.19 (8.7) | 0.10 / 0.79 / 0.11 |
TOTAL | 8309 | -- | -- | 7366 | -- | -- |