Table 2 Two-way ANOVA of strain background and age effects on phospho-tau burden in 6.5 and 10.5Â month-old rTg4510 B6 mice compared to rTg4510 mice
From: Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model
| Â | Strain background | Age | Interaction | |||
|---|---|---|---|---|---|---|
Region stain | F(DFn, DFd) | P value | F(DFn, DFd) | P value | F(DFn, DFd) | P value |
Cortex CP13 | F (1, 13) = 8.60 | P < 0.05 | F (1, 13) = 0.08 | P = 0.78 | F (1, 13) = 8.40 | P < 0.05 |
Cortex PHF1 | F (1, 13) = 9.20 | P < 0.001 | F (1, 13) = 0.05 | P = 0.83 | F (1, 13) = 9.40 | P < 0.001 |
Hipp CP13 | F (1, 13) = 15.00 | P < 0.01 | F (1, 13) = 0.05 | P = 0.83 | F (1, 13) = 1.00 | P = 0.33 |
Hipp PHF1 | F (1, 13) = 23.00 | P < 0.001 | F (1, 13) = 0.03 | P = 0.88 | F (1, 13) = 1.40 | P = 0.26 |
BS CP13 | F (1, 13) = 1.20 | P = 0.29 | F (1, 13) = 9.90 | P < 0.01 | F (1, 13) = 2.80 | P = 0.12 |
BS PHF1 | F (1, 13) = 21.00 | P < 0.001 | F (1, 13) = 1.10 | P = 0.32 | F (1, 13) = 0.43 | P = 0.52 |