Table 2 Putative cholinergic PPTg neurons’ basal firing and action potential waveforms in V + D and L + D rats. Neurons were categorized post-hoc by their responses to CNO, which was defined as ‘increase’ (firing rate during + CNO phase was ≥ 200 % compared to the rate during -CNO phase), ‘no change’ (during + CNO, firing rate was 50–200 % compared to during -CNO) or ‘decrease’ (during + CNO, firing rate was ≤ 50 % compared to during -CNO). The AP shape is classified as positive, meaning that the voltage deflection occurred upwards, negative, meaning that the voltage deflection occurred downwards, or bipolar, where voltage deflections occurred both up- and downwards
Group | Response type | n | AP shape | Basal firing Hz (Median and range) | ||
|---|---|---|---|---|---|---|
Negative | Positive | Bipolar | ||||
V + D | Excitation | 9 (24 %) | 9 | 0 | 0 | 5.75 Hz (0.3–24.2) |
No response | 24 (63 %) | 20 | 3 | 1 | 5.473 (0.4–49.3) | |
Inhibition | 5 (13 %) | 4 | 1 | 0 | 3.13 (0.4–31.6) | |
L + D | Excitation | 4 (17 %) | 2 | 2 | 0 | 4.09 (0.3–8.8) |
No response | 12 (52 %) | 11 | 1 | 0 | 10.84 (0.6–83.4) | |
Inhibition | 7 (30 %) | 6 | 1 | 0 | 7.08 (2.3–62.3) | |