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Fig. 6 | Molecular Neurodegeneration

Fig. 6

From: Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

Fig. 6

Memory is affected in mice treated with excess L-methionine for 10 weeks. a i Memory flexibility tests were performed for four consecutive days in the L-methionine group (black bars) and the control group (white bars). ii Measurements of average velocity. b i Open field tests were performed by the control and L-methionine groups. ii Representative trajectories of control and L-methionine mice in open field tests (n ≥ 12) c i The novel object recognition (NOR) test was performed by control (white bar) and L-methionine (black bar) animals. ii NOR representative traces of control and L-methionine mice; red circles indicate the position of the old object, while green circles indicate the position of the new object. Bars are mean ± SEM. *P < 0.05; **P < 0.01, ***P < 0.001

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