Fig. 1

Oral glutamine supplementation increases non-fasting blood glutamine concentrations in Atm ^−/− mice. Atm ^−/− mice (green or blue symbols) have significantly lower glutamine blood glutamine compared to age-matched wild type mice (purple or red symbols). Glutamine supplementation significantly improves the blood glutamine deficit of Atm ^−/− mice but has no effect on wild type mice. Symbols with a white square inside indicate female mice. Statistically different by two-tailed t-test: **, p < 0.01; *, p < 0.05; n.s. (not significant) p ≥ 0.05