Table 1 Characteristics of human samples
Regions sampled and source | Inferior frontal lobe (ROSMAP, RUSH ADRC) | |||
|---|---|---|---|---|
Clinical diagnosis | AD dementia | AD dementia | NCI | NCI |
Genotype | E3/E3 | E3/E4 | E3/E3 | E3/E4 |
Sample size, n | 12 | 10 | 12 | 10 |
Age at death (years ± SD) a | 92 ± 6 | 95 ± 5 | 83 ± 5 | 85 ± 4 |
Sex (n, female/male) a | 5/7 | 6/4 | 6/6 | 5/5 |
Braak stage | ||||
I | 1 | 0 | 0 | 0 |
II | 2 | 0 | 2 | 3 |
III | 3 | 0 | 5 | 2 |
IV | 0 | 0 | 4 | 5 |
V | 6 | 10 | 1 | 0 |